Multidrug efflux pumps: structure, function and regulation
Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly
throughout the world and threaten to become untreatable. The origins of resistance are …
throughout the world and threaten to become untreatable. The origins of resistance are …
Bacterial resistance to antimicrobial agents
Bacterial pathogens as causative agents of infection constitute an alarming concern in the
public health sector. In particular, bacteria with resistance to multiple antimicrobial agents …
public health sector. In particular, bacteria with resistance to multiple antimicrobial agents …
Structure, assembly, and function of tripartite efflux and type 1 secretion systems in gram-negative bacteria
Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …
organisms are diverse in function, energization, and structural organization. They form …
The food production environment and the development of antimicrobial resistance in human pathogens of animal origin
Food-borne pathogens are a serious human health concern worldwide, and the emergence
of antibiotic-resistant food pathogens has further confounded this problem. Once-highly …
of antibiotic-resistant food pathogens has further confounded this problem. Once-highly …
Functional and structural roles of the major facilitator superfamily bacterial multidrug efflux pumps
Pathogenic microorganisms that are multidrug-resistant can pose severe clinical and public
health concerns. In particular, bacterial multidrug efflux transporters of the major facilitator …
health concerns. In particular, bacterial multidrug efflux transporters of the major facilitator …
[HTML][HTML] Biochemical and molecular mechanisms of antibiotic resistance in Salmonella spp.
R Chaudhari, K Singh, P Kodgire - Research in Microbiology, 2023 - Elsevier
Salmonella is a diverse Gram-negative bacterium that represents the major disease burden
worldwide. According to WHO, Salmonella is one of the fourth global causes of diarrhoeal …
worldwide. According to WHO, Salmonella is one of the fourth global causes of diarrhoeal …
The Major Facilitator Superfamily and Antimicrobial Resistance Efflux Pumps of the ESKAPEE Pathogen Staphylococcus aureus
The ESKAPEE bacterial pathogen Staphylococcus aureus has posed a serious public
health concern for centuries. Throughout its evolutionary course, S. aureus has developed …
health concern for centuries. Throughout its evolutionary course, S. aureus has developed …
Epidemiology of efflux pumps genes mediating resistance among Staphylococcus aureus; A systematic review
Background Efflux of antibiotics is an effective resistance mechanism among antibiotic-
resistant Staphylococcus aureus. This systematic review aims to evaluate the frequency and …
resistant Staphylococcus aureus. This systematic review aims to evaluate the frequency and …
Inhibition of multidrug efflux pumps belonging to the major facilitator superfamily in bacterial pathogens
Bacterial pathogens resistant to multiple structurally distinct antimicrobial agents are
causative agents of infectious disease, and they thus constitute a serious concern for public …
causative agents of infectious disease, and they thus constitute a serious concern for public …
Promising FDA-approved drugs with efflux pump inhibitory activities against clinical isolates of Staphylococcus aureus
SAAM Abdel-Karim, AMA El-Ganiny, MA El-Sayed… - Plos one, 2022 - journals.plos.org
Background and objectives Staphylococcus aureus is an opportunistic pathogen that causes
wide range of nosocomial and community-acquired infections which have spread worldwide …
wide range of nosocomial and community-acquired infections which have spread worldwide …