Cocrystallization is an old technique and remains the focus of several research groups
working in the field of Chemistry and Pharmacy. This technique is basically in field for …

Pharmaceutical cocrystals represent a distinctive class of crystal engineered
multicomponent systems consisting an API and a crystal former non-covalently linked …

New theoretical screening procedure was proposed for appropriate selection of potential
cocrystal formers possessing the ability of enhancing dissolution rates of drugs. The …

A rational coformer screening methodology was adopted to identify new multicomponent
solid preformulations of the 2-aryl propionate class of nonsteroidal anti-inflammatory drugs …

Water solubility and low bioavailability of active pharmaceutical ingredients are some of the
main challenges in the process of developing new drugs, especially drugs in oral solid …

Most of the widely used drugs have problems associated with their oral bioavailability either
due to their poor aqueous solubility or due to their poor permeability. Co-crystallization is an …

Objective: Cocrystallisation is a promising method in order to increase the solubility and
dissolution of poorly water-soluble drugs. The aim of this study was to prepare, formulate …

Metaxalone is oxazolidin-2-one derivative, biopharmaceutics classification system class II
drug, available in the market as a central muscle relaxant drug, used to alleviate discomforts …

Objective: The solubility of a drug in water plays an important role in the absorption of the
drug after oral administration. Cocrystal is one method that improves the solubility of the …

A Carvedilol is a member of BCS class II, it has a low solubility and bioavailability. This work
intends to increase the solubility of carvedilol using a multicomponent crystal method. Based …