Despite significant advances in the understanding of cancer biology, cancer is still a leading
cause of death worldwide. Expression of the tumor microenvironment component …

KRAS mutation is the most frequent oncogenic aberration in colorectal cancer (CRC). The
molecular mechanism and clinical implications of KRAS mutation in CRC remain unclear …

Objective: Lung adenocarcinoma (LUAD) is a common malignant tumor with a poor
prognosis. The present study aimed to screen the key genes involved in LUAD development …

Background: EGFR mutations are present in approximately 15–50% of non-small cell lung
cancer (NSCLC), which are predictive of anti-EGFR therapies. At variance, NSCLC patients …

Objective To explore the expression of secreted phosphoprotein 1 (SPP1) in lung
adenocarcinoma (LUAD), and evaluate its relationship with clinicopathological …

Lung adenocarcinoma (LUAD) is a tumor with high incidence. This study aimed to identify
the central genes of LUAD. LUAD were analyzed by weighted gene co-expression network …

Despite intensive toxicological studies of carbon nanotubes (CNTs) over the last two
decades, only a few studies have demonstrated their pulmonary carcinogenicities in chronic …

The study evaluated whether SPP1/osteopontin (OPN) splice variants are differentially
expressed in nonmelanoma skin cancer compared to normal skin. The absolute number of …

Background: Osteopontin (OPN) splice variants are identified as predictors of tumour
progression and therapeutic resistance in certain types of solid tumours. However, their …

Abstract Ethnopharmacological relevance Euonymus alatus (Thunb.) Siebold (family
Celastraceae) is a deciduous woody shrub that is recorded in ShenNong BenCaoJing. It has …