The MEROPS website (http://merops. sanger. ac. uk) includes information on peptidase
inhibitors as well as on peptidases and their substrates. Displays have been put in place to …

Abstract Proprotein Convertases (PCs) are serine endoproteases that regulate the
homeostasis of protein substrates in the cell. The PCs family counts 9 members—PC1/3 …

Arenaviruses merit interest as clinically important human pathogens and include several
causative agents, chiefly Lassa virus (LASV), of hemorrhagic fever disease in humans …

Dengue virus (DENV) infection has evolved into a major global health menace and
economic burden due to its intensity and geographic distribution. DENV infection in humans …

Several arenaviruses cause hemorrhagic fever (HF) in humans, and evidence indicates that
the worldwide-distributed prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) is …

The biochemical mechanism controlling nucleation of mineral crystals in developing bone,
along with the growth and propagation of these crystals once formed, remains poorly …

Glucantime (SbV) is the first-line treatment against American Tegumentary Leishmaniasis.
Resistance cases to this drug have been reported and related to host characteristics and …

The mammalian proprotein convertase subtilisin kexins (PCSKs) previously called
proprotein or prohormone convertases (PCs) are a family of Ca+ 2-dependent …

Human site-1-protease (S1P, MEROPS S08. 8063), also widely known as subtilisin/kexin
isozyme 1 (SKI-1), is a membrane bound subtilisin-related serine protease, that belongs to a …

The proprotein convertases PCSK8 and PCSK4 are, respectively, the 8th and 4th members
of Ca+ 2-dependent serine endoprotease of Proprotein Convertase Subtilisin Kexin (PCSK) …