Controversies in the pathogenesis, diagnosis and treatment of PCOS: focus on insulin resistance, inflammation, and hyperandrogenism

D Armanini, M Boscaro, L Bordin… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is a heterogeneous and extremely common disease with
symptoms that vary with the age of the patient, typically characterized by hyperandrogenism …

Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies

R Kaur, M Kaur, J Singh - Cardiovascular diabetology, 2018 - Springer
The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …

Triglyceride-glucose index and triglyceride to high-density lipoprotein cholesterol ratio as potential cardiovascular disease risk factors: an analysis of UK biobank data

B Che, C Zhong, R Zhang, L Pu, T Zhao… - Cardiovascular …, 2023 - Springer
Abstract Background The triglyceride-glucose (TyG) index and triglyceride to high-density
lipoprotein cholesterol (TG/HDL-C) ratio, two simple surrogate indicators of insulin …

Epidemiology of chronic liver diseases in the USA in the past three decades

ZM Younossi, M Stepanova, Y Younossi, P Golabi… - Gut, 2020 - gut.bmj.com
Objective Given significant advances in treatment of viral hepatitis and the growing epidemic
of obesity, the burden of the different types of liver diseases in the USA may be changing …

Comprehensive genetic study of the insulin resistance marker TG: HDL-C in the UK Biobank

A Oliveri, RJ Rebernick, A Kuppa, A Pant, Y Chen… - Nature …, 2024 - nature.com
Insulin resistance (IR) is a well-established risk factor for metabolic disease. The ratio of
triglycerides to high-density lipoprotein cholesterol (TG: HDL-C) is a surrogate marker of IR …

Time‐restricted eating effects on body composition and metabolic measures in humans who are overweight: a feasibility study

LS Chow, ENC Manoogian, A Alvear, JG Fleischer… - …, 2020 - Wiley Online Library
Objective In contrast to intentionally restricting energy intake, restricting the eating window
may be an option for treating obesity. By comparing time‐restricted eating (TRE) with an …

Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it the opposite?

JI Malone, BC Hansen - Pediatric diabetes, 2019 - Wiley Online Library
Obesity is believed to be a promoter of type 2 diabetes mellitus (T2DM). Reports indicate
that severe obesity in childhood and adolescence increases the risk of T2DM in youth and …

The epidemiology of cirrhosis in the United States: a population-based study

S Scaglione, S Kliethermes, G Cao… - Journal of clinical …, 2015 - journals.lww.com
Methods: National Health And Nutrition Examination Survey data conducted between 1999
and 2010 were used to estimate cirrhosis prevalence and factors associated with cirrhosis …

Association between macro-and microvascular damage and the triglyceride glucose index in community-dwelling elderly individuals: the Northern Shanghai Study

S Zhao, S Yu, C Chi, X Fan, J Tang, H Ji… - Cardiovascular …, 2019 - Springer
Background It has been reported that the triglyceride-glucose (TyG) index may serve as a
simple and credible surrogate marker of insulin resistance (IR). However, its association with …

Effects of aerobic and resistance exercise on metabolic syndrome, sarcopenic obesity, and circulating biomarkers in overweight or obese survivors of breast cancer: a …

CM Dieli-Conwright, KS Courneya… - Journal of Clinical …, 2018 - ascopubs.org
Purpose Metabolic syndrome is associated with an increased risk of cardiovascular disease,
type 2 diabetes, and breast cancer recurrence in survivors of breast cancer. This …