Background Vasculogenic mimicry (VM) is a recently discovered angiogenetic process
found in many malignant tumors, and is different from the traditional angiogenetic process …

The discovery of RNA interference, first in plants and Caenorhabditis elegans and later in
mammalian cells, led to the emergence of a transformative view in biomedical research …

The gene-expression profile of aggressive cutaneous and uveal melanoma cells resembles
that of an undifferentiated, embryonic-like cell. The plasticity of certain types of cancer cell …

Tumour blood vessels express markers that are not present in resting blood vessels of
normal tissues, but that can be shared by angiogenic vessels in non-malignant conditions …

More than 25 years of research and preclinical validation have defined EphA2 receptor
tyrosine kinase as a promising molecular target for clinical translation in cancer treatment …

Vasculogenic mimicry (VM) is a blood supply system independent of endothelial vessels in
tumor cells from different origins. It reflects the plasticity of aggressive tumor cells that …

Vasculogenic mimicry (VM) is a brand‐new tumour vascular paradigm independent of
angiogenesis that describes the specific capacity of aggressive cancer cells to form vessel …

In 1999, The American Journal of Pathology published an article entitled “Vascular Channel
Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry,” by …

Bidirectional cellular communication is integral to both cancer progression and
embryological development. In addition, aggressive tumor cells are phenotypically plastic …

Vasculogenic mimicry describes a process where aggressive tumor cells in three-
dimensionalmatrices mimic embryonic vasculogenesis by forming extracellular matrix (ECM) …