Injectable alginate hydrogels for cell delivery in tissue engineering

SJ Bidarra, CC Barrias, PL Granja - Acta biomaterialia, 2014 - Elsevier
Alginate hydrogels are extremely versatile and adaptable biomaterials, with great potential
for use in biomedical applications. Their extracellular matrix-like features have been key …

Biodegradable biomatrices and bridging the injured spinal cord: the corticospinal tract as a proof of principle

EAJ Joosten - Cell and tissue research, 2012 - Springer
Important advances in the development of smart biodegradable implants for axonal
regeneration after spinal cord injury have recently been reported. These advances are …

Sensory neurons and osteoblasts: close partners in a microfluidic platform

E Neto, CJ Alves, DM Sousa, IS Alencastre… - Integrative …, 2014 - academic.oup.com
Innervation has proven to be critical in bone homeostasis/regeneration due to the effect of
soluble factors, produced by nerve fibers, associated with changes in the activity of bone …

Alginate–hydroxyapatite bone scaffolds with isotropic or anisotropic pore structure: material properties and biological behavior

D Porrelli, A Travan, G Turco, E Marsich… - Macromolecular …, 2015 - Wiley Online Library
Alginate/hydroxyapatite composites, with isotropic or anisotropic porosity, were developed
using two different freezing methods. Morphological analysis highlighted the differences in …

The sulfation of biomimetic glycosaminoglycan substrates controls binding of growth factors and subsequent neural and glial cell growth

W Malaeb, HF Bahmad, W Abou-Kheir… - Biomaterials …, 2019 - pubs.rsc.org
Sulfated glycosaminoglycans (GAGs) are key structural and functional extracellular matrix
(ECM) molecules involved in numerous signaling pathways mainly through their interaction …

Alginate sulfate substrates control growth factor binding and growth of primary neurons: Toward engineered 3D neural networks

G Kfoury, V El Habbaki, W Malaeb… - Advanced …, 2020 - Wiley Online Library
Sulfated glycosaminoglycans (sGAGs) are vital molecules of the extracellular matrix (ECM)
of the nervous system known to regulate proliferation, migration, and differentiation of …

Biomimetic sulfated glycosaminoglycans maintain differentiation markers of breast epithelial cells and preferentially inhibit proliferation of cancer cells

Z Habli, NN Al Deen, W Malaeb, N Mahfouz… - Acta Biomaterialia, 2021 - Elsevier
Glycosaminoglycans (GAG) are key elements involved in various physiological and
pathological processes including cancer. Several GAG-based drugs have been developed …

Speculations on the use of marine polysaccharides as scaffolds for artificial nerve 'side-'grafts

SM Amr, B Ekram - Biological activities and application of marine …, 2017 - books.google.com
Marine polysaccharides (eg, chitosan, alginate and agarose) meet the requirements of
artificial nerve grafting. These include the following:(1) prerequisites of biopolymers used as …

Spinal cord repair by means of tissue engineered scaffolds

M Wang, X Chen, DJ Schreyer - Emerging Trends in Cell and Gene …, 2013 - Springer
Spinal cord injury (SCI) leads to devastating and permanent loss of neurological function,
affecting all levels below the site of trauma. The injured adult spinal cord has little self …