Cancer is a group of cells that malignantly grow and proliferate uncontrollably. At present,
treatment modes for cancer mainly comprise surgery, chemotherapy, radiotherapy …

Noncanonical NF-κB signaling differs from canonical NF-κB signaling by being activated
through different cell surface receptors, cytoplasmic adaptors, and NF-κB dimers. Under …

Definitive haematopoiesis in the fetal liver supports self-renewal and differentiation of
haematopoietic stem cells and multipotent progenitors (HSC/MPPs) but remains poorly …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection often causes
severe complications and even death. However, asymptomatic infection has also been …

Since the discovery of the nuclear factor kappa B (NF-ĸB) transcription factor 36 years ago,
many studies have linked the NF-ĸB signaling pathway to pathological and physiological …

NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was
identified as a pivotal pathway in mediating inflammatory responses. However, with …

The emergence of immunotherapies has definitely proven the tight relationship between
malignant and immune cells, its impact on cancer outcome and its therapeutic potential. In …

The synovium is an important component of any synovial joint and is the major target tissue
of inflammatory arthritis. However, the multi-omics landscape of synovium required for …

Nuclear Factor-Κappa B (NF-ΚB) is a family of critical transcription factors of the
inflammatory pathway and plays an imperative role in the progression of various cancers …

B-cell receptor (BCR) is a B cell hallmark surface complex regulating multiple cellular
processes in normal as well as malignant B cells. Igα (CD79a)/Igβ (CD79b) are essential …