Global burden of liver disease: 2023 update

H Devarbhavi, SK Asrani, JP Arab, YA Nartey… - Journal of …, 2023 - Elsevier
Liver disease accounts for two million deaths annually and is responsible for 4% of all
deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related …

[HTML][HTML] Global epidemiology of cirrhosis—aetiology, trends and predictions

DQ Huang, NA Terrault, F Tacke, LL Gluud… - Nature reviews …, 2023 - nature.com
Cirrhosis is an important cause of morbidity and mortality in people with chronic liver
disease worldwide. In 2019, cirrhosis was associated with 2.4% of global deaths. Owing to …

Gut-liver axis: Pathophysiological concepts and clinical implications

H Tilg, TE Adolph, M Trauner - Cell metabolism, 2022 - cell.com
Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …

[HTML][HTML] Global incidence and prevalence of nonalcoholic fatty liver disease

MLP Teng, CH Ng, DQ Huang, KE Chan… - Clinical and …, 2023 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver disease worldwide. The
estimated global incidence of NAFLD is 47 cases per 1,000 population and is higher among …

Lifestyle interventions in nonalcoholic fatty liver disease

ZM Younossi, S Zelber-Sagi, L Henry… - Nature Reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a dynamic chronic liver disease that develops in
close association with metabolic irregularities. Between 2016 and 2019, the global …

EASL Clinical Practice Guidelines on sclerosing cholangitis

O Chazouilleres, U Beuers, A Bergquist, TH Karlsen… - Journal of …, 2022 - Elsevier
Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

Global epidemiology and genetics of hepatocellular carcinoma

MR Toh, EYT Wong, SH Wong, AWT Ng, LH Loo… - Gastroenterology, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is one of the leading cancers worldwide. Classically, HCC
develops in genetically susceptible individuals who are exposed to risk factors, especially in …

Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

[HTML][HTML] Health disparities in chronic liver disease

A Kardashian, M Serper, N Terrault, LD Nephew - Hepatology, 2023 - journals.lww.com
The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to
important changes in liver disease epidemiology that have exacerbated health disparities …

Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses

MM Lane, E Gamage, S Du, DN Ashtree… - bmj, 2024 - bmj.com
Objective To evaluate the existing meta-analytic evidence of associations between exposure
to ultra-processed foods, as defined by the Nova food classification system, and adverse …