The combination of laser photodissociation, action spectroscopy, and mass spectrometry to identify and separate isomers
SJP Marlton, AJ Trevitt - Chemical Communications, 2022 - pubs.rsc.org
The separation and detection of isomers remains a challenge for many areas of mass
spectrometry. This article highlights laser photodissociation and ion mobility strategies that …
spectrometry. This article highlights laser photodissociation and ion mobility strategies that …
Lipid analysis by mass spectrometry coupled with laser light
C Kirschbaum, K Pagel - Analysis & Sensing, 2023 - Wiley Online Library
Lipids are small but complex biomolecules that feature an immense structural and functional
diversity. The molecular structure and biological functions of lipids are intricately linked …
diversity. The molecular structure and biological functions of lipids are intricately linked …
Mass-spectrometry-based identification of synthetic drug isomers using infrared ion spectroscopy
RF Kranenburg, FAMG van Geenen, G Berden… - Analytical …, 2020 - ACS Publications
Infrared ion spectroscopy (IRIS), a mass-spectrometry-based technique exploiting resonant
infrared multiple photon dissociation (IRMPD), has been applied for the identification of …
infrared multiple photon dissociation (IRMPD), has been applied for the identification of …
Amadori rearrangement products as potential biomarkers for inborn errors of amino-acid metabolism
The identification of disease biomarkers plays a crucial role in developing diagnostic
strategies for inborn errors of metabolism and understanding their pathophysiology. A …
strategies for inborn errors of metabolism and understanding their pathophysiology. A …
Isomer-Specific Two-Color Double-Resonance IR2MS3 Ion Spectroscopy Using a Single Laser: Application in the Identification of Novel Psychoactive Substances
FAMG van Geenen, RF Kranenburg… - Analytical …, 2021 - ACS Publications
The capability of an ion trap mass spectrometer to store ions for an arbitrary amount of time
allows the use of a single infrared (IR) laser to perform two-color double resonance IR–IR …
allows the use of a single infrared (IR) laser to perform two-color double resonance IR–IR …
Evaluation of table-top lasers for routine infrared ion spectroscopy in the analytical laboratory
RE van Outersterp, J Martens, A Peremans, L Lamard… - Analyst, 2021 - pubs.rsc.org
Infrared ion spectroscopy is increasingly recognized as a method to identify mass
spectrometry-detected analytes in many (bio) chemical areas and its integration in analytical …
spectrometry-detected analytes in many (bio) chemical areas and its integration in analytical …
Targeted Small-Molecule Identification Using Heartcutting Liquid Chromatography–Infrared Ion Spectroscopy
RE van Outersterp, J Oosterhout, CR Gebhardt… - Analytical …, 2023 - ACS Publications
Infrared ion spectroscopy (IRIS) can be used to identify molecular structures detected in
mass spectrometry (MS) experiments and has potential applications in a wide range of …
mass spectrometry (MS) experiments and has potential applications in a wide range of …
Preferred protonation site of a series of sulfa drugs in the gas phase revealed by IR spectroscopy
Sulfa drugs are an important class of pharmaceuticals in the treatment of bacterial infections.
The amido/imido tautomerism of these molecules in their neutral form has been widely …
The amido/imido tautomerism of these molecules in their neutral form has been widely …
[HTML][HTML] High-Throughput UV Photoionization and Fragmentation of Neutral Biomolecules as a Structural Fingerprint
S Wang, Y Dauletyarov, DA Horke - Molecules, 2023 - mdpi.com
We present UV photofragmentation studies of the structural isomers paracetamol, 3-
Pyridinepropionic acid (3-PPIA) and (R)-(-)-2-Phenylglycine. In particular, we utilized a new …
Pyridinepropionic acid (3-PPIA) and (R)-(-)-2-Phenylglycine. In particular, we utilized a new …
Instrument-independent chemometric models for rapid, calibration-free NPS isomer differentiation from mass spectral GC-MS data
JL Bonetti, RF Kranenburg, E Schoonderwoerd… - Forensic Science …, 2023 - Elsevier
Chemometric analysis of mass spectral data for the purpose of differentiating positional
isomers of novel psychoactive substances has seen a substantial increase in popularity in …
isomers of novel psychoactive substances has seen a substantial increase in popularity in …