Rhythms of life: circadian disruption and brain disorders across the lifespan
RW Logan, CA McClung - Nature Reviews Neuroscience, 2019 - nature.com
Many processes in the human body—including brain function—are regulated over the 24-
hour cycle, and there are strong associations between disrupted circadian rhythms (for …
hour cycle, and there are strong associations between disrupted circadian rhythms (for …
Impact of sleep and circadian rhythms on addiction vulnerability in adolescents
Sleep homeostasis and circadian function are important maintaining factors for optimal
health and well-being. Conversely, sleep and circadian disruptions are implicated in a …
health and well-being. Conversely, sleep and circadian disruptions are implicated in a …
Neurobiological and behavioral mechanisms of circadian rhythm disruption in bipolar disorder: a critical multi‐disciplinary literature review and agenda for future …
MJ McCarthy, JF Gottlieb, R Gonzalez… - Bipolar …, 2022 - Wiley Online Library
Aim Symptoms of bipolar disorder (BD) include changes in mood, activity, energy, sleep,
and appetite. Since many of these processes are regulated by circadian function, circadian …
and appetite. Since many of these processes are regulated by circadian function, circadian …
Regulation and function of extra‐SCN circadian oscillators in the brain
K Begemann, AM Neumann, H Oster - Acta physiologica, 2020 - Wiley Online Library
Most organisms evolved endogenous, so called circadian clocks as internal timekeeping
mechanisms allowing them to adapt to recurring changes in environmental demands …
mechanisms allowing them to adapt to recurring changes in environmental demands …
Circadian clock genes: effects on dopamine, reward and addiction
Addiction is a widespread public health issue with social and economic ramifications.
Substance abuse disorders are often accompanied by disruptions in circadian rhythms …
Substance abuse disorders are often accompanied by disruptions in circadian rhythms …
Disrupted sleep and circadian rhythms in schizophrenia and their interaction with dopamine signaling
A Ashton, A Jagannath - Frontiers in neuroscience, 2020 - frontiersin.org
Sleep and circadian rhythm disruption (SCRD) is a common feature of schizophrenia, and is
associated with symptom severity and patient quality of life. It is commonly manifested as …
associated with symptom severity and patient quality of life. It is commonly manifested as …
Astrocyte molecular clock function in the nucleus accumbens is important for reward-related behavior
Background Substance use disorders are associated with disruptions in circadian rhythms.
Both human and animal work have shown the integral role for circadian clocks in the …
Both human and animal work have shown the integral role for circadian clocks in the …
The ventral tegmental area and nucleus accumbens as circadian oscillators: implications for drug abuse and substance use disorders
Circadian rhythms convergently evolved to allow for optimal synchronization of individuals'
physiological and behavioral processes with the Earth's 24-h periodic cycling of …
physiological and behavioral processes with the Earth's 24-h periodic cycling of …
The role of CLOCK gene in psychiatric disorders: Evidence from human and animal research
JB Schuch, JP Genro, CR Bastos… - American Journal of …, 2018 - Wiley Online Library
The circadian clock system drives daily rhythms in physiology, metabolism, and behavior in
mammals. Molecular mechanisms of this system consist of multiple clock genes, with …
mammals. Molecular mechanisms of this system consist of multiple clock genes, with …
Molecular mechanisms in mood regulation involving the circadian clock
U Albrecht - Frontiers in neurology, 2017 - frontiersin.org
The circadian system coordinates activities and functions in cells and tissues in order to
optimize body functions in anticipation to daily changes in the environment. Disruption of the …
optimize body functions in anticipation to daily changes in the environment. Disruption of the …