Hesperidin mitigates cyclophosphamide-induced testicular dysfunction via altering the hypothalamic pituitary gonadal axis and testicular steroidogenesis …

T Khamis, AA Hegazy, SSA El-Fatah, ER Abdelfattah… - Pharmaceuticals, 2023 - mdpi.com
Cyclophosphamide (CP) is a cytotoxic, cell cycle, non-specific, and antiproliferative drug.
This study aimed to address the toxic effects of CP on male fertility and the possible …

Nobiletin ameliorates nonylphenol-induced testicular damage by improving biochemical, steroidogenic, hormonal, spermatogenic, apoptotic and histological profile

MU Ijaz, A Tahir, A Samad… - Human & Experimental …, 2021 - journals.sagepub.com
Nonylphenol (NP) is an environmental contaminant, which adversely affects the male fertility
due to endocrine disruption and generation of oxidative stress. The current research was …

Sciadopitysin mitigates spermatological and testicular damage instigated by paraquat administration in male albino rats

MU Ijaz, M Qamer, A Hamza, H Ahmed, T Afsar… - Scientific reports, 2023 - nature.com
Paraquat (PQ) is a herbicide that has ability to induce testicular toxicity by producing reactive
oxygen species (ROS). Sciadopitysin (SPS) is a promising flavonoid that displays multiple …

[HTML][HTML] Chemoprotective effect of vitexin against cisplatin-induced biochemical, spermatological, steroidogenic, hormonal, apoptotic and histopathological damages …

MU Ijaz, A Tahir, H Ahmed, A Ashraf… - Saudi Pharmaceutical …, 2022 - Elsevier
Cisplatin (CP) is one of the most widely used antineoplastic drugs, which possesses the
potential to treat a variety of malignancies. However, it displays numerous side effects as …

Mechanistic insight into the protective effects of fisetin against arsenic-induced reproductive toxicity in male rats

MU Ijaz, S Haider, A Tahir, T Afsar, A Almajwal… - Scientific reports, 2023 - nature.com
Arsenic is one of the most hazardous environmental contaminants, which adversely affects
the dynamics of male reproductive system. Fisetin (FIS) is a bioactive flavonoid, which is …

[HTML][HTML] Pachypodol attenuates Perfluorooctane sulphonate-induced testicular damage by reducing oxidative stress

MU Ijaz, A Rauf, S Mustafa, H Ahmed, A Ashraf… - Saudi journal of …, 2022 - Elsevier
Perfluorooctane sulfonate (PFOS) is an endocrine disruptor chemical (EDC) with potentially
adverse effects on the male reproductive system. Pachypodol (5, 4′-dihydroxy-3, 7, 3 …

[HTML][HTML] Evaluation of possible palliative role of tamarixetin against cisplatin-induced renal toxicity by modulation of oxidative stress, inflammation and apoptosis in rats

MU Ijaz, MF Hayat, BO Almutairi, MH Almutairi… - Journal of King Saud …, 2023 - Elsevier
Cisplatin (CP) is a top-notch anti-cancerous agent that is used during the treatments of
various types of tumors. Tamarixetin (TM) is a naturally occurring polyphenolic compound …

[HTML][HTML] 210Protective Effect of Aloe vera Gel against Cisplatin-Induced Testicular Damage, Sperm Alteration and Oxidative Stress in Rats

NE Majd, MR Tabandeh, SH Hosseinifar… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Cisplatin (CIS) is an effective antineoplastic drug that is used to treat various
types of cancers. However, it causes side effects on the male reproductive system. The …

[HTML][HTML] Protective effects of vitexin on cadmium-induced renal toxicity in rats

MU Ijaz, M Batool, A Batool, KA Al-Ghanimd… - Saudi Journal of …, 2021 - Elsevier
Cadmium (Cd) is an industrial contaminant that poses severe threats to human and animal
health. Vitexin (VIT) is a polyphenolic flavonoid of characteristic pharmacological properties …

Rhamnazin ameliorates 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-evoked testicular toxicity by restoring biochemical, spermatogenic and histological profile in male albino …

MU Ijaz, S Mustafa, QU Ain… - Human & …, 2023 - journals.sagepub.com
2, 3, 7, 8 tetrachlorodibenzo-p-dioxin (TCDD) is a potential environmental toxin that has the
ability to affect male reproductive tract. Rhamnazin is a naturally present flavone that …