Cardiolipins (CLs) are specific phospholipids of the mitochondria composing about 20% of
the inner mitochondria membrane (IMM) phospholipid mass. Dysregulation of CL …

The MMPs and their inhibitors [tissue inhibitor of MMPs (TIMPs)] form the mainstay of
extracellular matrix homeostasis. They are expressed in response to numerous stimuli …

Oral squamous cell carcinoma (OSCC) forms the majority of the entire cancerous tumors
which occur in the mouth. Current treatment advances, such as surgical resection …

The transforming growth factor-β (TGF-β) signaling pathway is believed to contribute to
carcinoma development by increasing cell invasiveness and metastasis and inducing the …

Nuclear factor-κB (NF-κB) signaling contributes to human disease processes, notably
inflammatory diseases and cancer. NF-κB has a role in tumorigenesis and tumor growth, as …

Several cellular models of trophoblast have been proposed to understand their invasion. We
had reported that JEG-3 and HTR-8/SVneo cells show differential invasive behavior in …

Abstract Estrogen receptor (ER)-negative, progesterone receptor (PR)-negative and HER2-
negative, or “triple negative,” breast cancer (TNBC) is a poor prognosis clinical subtype that …

Breast cancer (BC) is the most common type of cancer diagnosed in women. Among female
cancer deaths, BC is the second leading cause of death worldwide. For estrogen receptor …

PPM1A (magnesium-dependent phosphatase 1 A, also known as PP2Cα) is a member of
the Ser/Thr protein phosphatase family. Protein phosphatases catalyze the removal of …

Osteosarcoma (OS) is identified as an aggressive malignancy of the skeletal system and
normally occurs among young people. It is well accepted that microRNAs are implicated in …