Plant intra-individual and inter-individual variation can be determined by the epigenome, a
set of covalent modifications of DNA and chromatin that can alter genome structure and …

DNA methylation (DNAme) and histone post-translational modifications (PTMs) have
important roles in transcriptional regulation. Although many reports have characterized the …

Constitutive heterochromatin, mainly formed at the gene-poor regions of pericentromeres, is
believed to ensure a condensed and transcriptionally inert chromatin conformation …

Chromatin provides both a means to accommodate a large amount of genetic material in a
small space and a means to package the same genetic material in different chromatin states …

Eukaryotic chromatin is kept flexible and dynamic to respond to environmental, metabolic,
and developmental cues through the action of a family of so-called “nucleosome …

Stability and function of eukaryotic genomes are closely linked to chromatin structure and
organization. During cell division the entire genome must be accurately replicated and the …

The opposing activities of 53BP1 and BRCA1 influence pathway choice in DNA double-
strand-break repair. How BRCA1 counteracts the inhibitory effect of 53BP1 on DNA …

Chromatin dynamics play an essential role in regulating the accessibility of genomic DNA for
a variety of nuclear processes, including gene transcription and DNA repair. The …

Several homology-dependent pathways can repair potentially lethal DNA double-strand
breaks (DSBs). The first step common to all homologous recombination reactions is the 5 …

Faithful transfer of parental histones to newly replicated daughter DNA strands is critical for
inheritance of epigenetic states. Although replication proteins that facilitate parental histone …