Generalized anxiety disorder (GAD) is a prevalent and chronic mental disorder that elicits
widespread functional impairment. Given the high degree of non-response/partial response …

The startle is a relatively simple ubiquitous reflex. Interestingly, it has a “non-zero baseline”,
ie, its magnitude can be reduced or enhanced. We reflect here on the translational value of …

Startle reflex potentiation versus startle attenuation to unpleasant versus pleasant stimuli
likely reflect priming of the defensive versus appetitive motivational systems, respectively …

Abstract Purpose of Review Neuroactive steroid hormones, such as estradiol and
progesterone, likely play a role in the pathophysiology of female-specific psychiatric …

This introduction presents an overview of the key concepts discussed in the subsequent
chapters of this book. The book explains why practitioners and agencies should consider …

Abstract 'Initial therapy contacts', defined as (the first) 3 h or less of face-to-face
psychological treatment, encompassing both the early phase of a longer therapy and one-off …

Conventional wisdom dictates we must face our fears to conquer them. This idea is
embodied in exposure-based treatments for anxiety disorders, where the intent of exposure …

Background: Rewind is a brief trauma-focussed imaginal exposure treatment for
posttraumatic stress disorder (PTSD), however evidence for this treatment is limited. Aim …

Despite being identified as a pervasive emotion in the modern workplace (Pfeffer & Sutton,
2000), fear oddly has not received a corresponding amount of attention among management …

Abstract Background The Research Domain Criteria (RDoC) has been developed as an
alternative approach to studying psychiatric disorders. The RDoC constructs and units of …