Cyclobutanes are increasingly used in medicinal chemistry in the search for relevant
biological properties. Important characteristics of the cyclobutane ring include its unique …

Tuberculosis (TB) was announced as a global emergency in 1993. There was an alarming
counter attack of TB worldwide. However, when it was known that TB can be cured …

Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis,
remains one of the leading causes of mortality across the world. There is an urgent …

Tuberculosis (TB) is a serious public health problem worldwide. Its situation is worsened by
the presence of multidrug resistant (MDR) strains of Mycobacterium tuberculosis, the …

Pyrazinamide (PZA) is a unique antituberculosis (anti-TB) drug that plays a key role in
shortening TB therapy. PZA kills nonreplicating persisters that other TB drugs fail to kill …

Tuberculosis (TB) remains one of the leading public health problems worldwide. Declared
as a global emergency in 1993 by the WHO, its control is hampered by the emergence of …

The purpose of this expert review is to discuss the impact of nanotechnology in the treatment
of the major health threats including cancer, infections, metabolic diseases, autoimmune …

Certain infectious diseases caused by pathogenic bacteria are typically chronic in nature.
Potentially deadly examples include tuberculosis, caused by Mycobacterium tuberculosis …

Drug resistance in tuberculosis (TB) is a particular problem because the lengthy therapy of
at least 6 months makes patient compliance very difficult, which frequently creates drug …

Rhodococcus sp. strain RHA1, a soil bacterium related to Mycobacterium tuberculosis,
degrades an exceptionally broad range of organic compounds. Transcriptomic analysis of …