Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …

With the trend of moving molecular tests from clinical laboratories to on-site testing, there is a
need for nucleic acid based diagnostic tools combining the sensitivity, specificity and …

Few methods for the detection of SARS‐CoV‐2 currently have the capability to
simultaneously detect two genes in a single test, which is a key measure to improve …

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-
associated (Cas) systems have revolutionized biological and biomedical sciences in many …

Viral infections are one of the most intimidating threats to human beings. One convincing
example is the coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2. Rapid …

Listeria monocytogenes is an important foodborne pathogen that can cause listeriosis with
high patient mortality. Accordingly, it is necessary to develop a L. monocytogenes detection …

Background In the context of the current pandemic caused by the novel coronavirus,
molecular detection is not limited to the clinical laboratory, but also faces the challenge of …

The development of a sensing platform with high sensitivity and specificity, especially
programmability and universal applicability, for the detection of clinically relevant molecules …

Nucleic acid biomarkers have been widely used to detect various viral-associated diseases,
including the recent pandemic COVID-19. The CRISPR-Cas-based trans-activating …

Recent advances in CRISPR based biotechnologies have greatly expanded our capabilities
to repurpose CRISPR for the development of biomolecular sensors for diagnosing diseases …