[HTML][HTML] Origin, development, and synaptogenesis of cortical interneurons
A Llorca, R Deogracias - Frontiers in Neuroscience, 2022 - frontiersin.org
The mammalian cerebral cortex represents one of the most recent and astonishing
inventions of nature, responsible of a large diversity of functions that range from sensory …
inventions of nature, responsible of a large diversity of functions that range from sensory …
Distinct molecular programs regulate synapse specificity in cortical inhibitory circuits
How neuronal connections are established and organized into functional networks
determines brain function. In the mammalian cerebral cortex, different classes of GABAergic …
determines brain function. In the mammalian cerebral cortex, different classes of GABAergic …
[HTML][HTML] Physiological and pathological roles of mammalian NEK7
Z Sun, W Gong, Y Zhang, Z Jia - Frontiers in physiology, 2020 - frontiersin.org
NEK7 is the smallest NIMA-related kinase (NEK) in mammals. The pathological and
physiological roles of NEK7 have been widely reported in many studies. To date, the major …
physiological roles of NEK7 have been widely reported in many studies. To date, the major …
[HTML][HTML] Vision-dependent specification of cell types and function in the developing cortex
The role of postnatal experience in sculpting cortical circuitry, while long appreciated, is
poorly understood at the level of cell types. We explore this in the mouse primary visual …
poorly understood at the level of cell types. We explore this in the mouse primary visual …
[HTML][HTML] Activity-dependent plasticity of axo-axonic synapses at the axon initial segment
The activity-dependent rules that govern the wiring of GABAergic interneurons are not well
understood. Chandelier cells (ChCs) are a type of GABAergic interneuron that control …
understood. Chandelier cells (ChCs) are a type of GABAergic interneuron that control …
[HTML][HTML] NEK7 regulates NLRP3 inflammasome activation and neuroinflammation post-traumatic brain injury
Y Chen, J Meng, F Bi, H Li, C Chang, C Ji… - Frontiers in molecular …, 2019 - frontiersin.org
As one of the most common causes of mortality and disability, traumatic brain injury (TBI) is a
huge psychological and economic burden to patients, families, and societies worldwide …
huge psychological and economic burden to patients, families, and societies worldwide …
CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity
W Guo, H Wang, A Kumar Tharkeshwar… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction The most common genetic cause of frontotemporal dementia (FTD) and
amyotrophic lateral sclerosis (ALS) are hexanucleotide repeats in chromosome 9 open …
amyotrophic lateral sclerosis (ALS) are hexanucleotide repeats in chromosome 9 open …
[HTML][HTML] Assessing transcriptome quality in patch-seq datasets
SJ Tripathy, L Toker, C Bomkamp… - Frontiers in Molecular …, 2018 - frontiersin.org
Patch-seq, combining patch-clamp electrophysiology with single-cell RNA-sequencing
(scRNAseq), enables unprecedented access to a neuron's transcriptomic …
(scRNAseq), enables unprecedented access to a neuron's transcriptomic …
[HTML][HTML] UNC-116 and UNC-16 function with the NEKL-3 kinase to promote axon targeting
CJ Drozd, CC Quinn - Development, 2023 - journals.biologists.com
ABSTRACT KIF5C is a kinesin-1 heavy chain that has been associated with
neurodevelopmental disorders. Although the roles of kinesin-1 in axon transport are well …
neurodevelopmental disorders. Although the roles of kinesin-1 in axon transport are well …
[HTML][HTML] NEK7 coordinates rapid neuroinflammation after subarachnoid hemorrhage in mice
G Li, Y Dong, D Liu, Z Zou, G Hao, X Gao, P Pan… - Frontiers in …, 2020 - frontiersin.org
Background: Subarachnoid hemorrhage (SAH) is a devastating disease which leads to high
morbidity and mortality. Recent studies have indicated that, never in mitosis gene A-related …
morbidity and mortality. Recent studies have indicated that, never in mitosis gene A-related …