A new Leishmania-specific hypothetical protein and its non-described specific B cell conformational epitope applied in the serodiagnosis of canine visceral …
DP Lage, VT Martins, MC Duarte, LE Costa… - Parasitology …, 2016 - Springer
The serodiagnosis of canine visceral leishmaniasis (CVL) presents problems related to its
sensitivity and/or specificity. In the present study, a new Leishmania-specific hypothetical …
sensitivity and/or specificity. In the present study, a new Leishmania-specific hypothetical …
[HTML][HTML] A large-scale field randomized trial demonstrates safety and efficacy of the vaccine LetiFend® against canine leishmaniosis
JF Cotrina, V Iniesta, I Monroy, V Baz, C Hugnet… - Vaccine, 2018 - Elsevier
Canine leishmaniosis is a zoonotic disease caused by Leishmania infantum. Extensive
research is currently ongoing to develop safe and effective vaccines to protect from disease …
research is currently ongoing to develop safe and effective vaccines to protect from disease …
Identification of Proteins in Promastigote and Amastigote-like Leishmania Using an Immunoproteomic Approach
VTS Coelho, JS Oliveira, DG Valadares… - PLoS Neglected …, 2012 - journals.plos.org
Background The present study aims to identify antigens in protein extracts of promastigote
and amastigote-like Leishmania (Leishmania) chagasi syn. L.(L.) infantum recognized by …
and amastigote-like Leishmania (Leishmania) chagasi syn. L.(L.) infantum recognized by …
Theranostic applications of phage display to control leishmaniasis: selection of biomarkers for serodiagnostics, vaccination, and immunotherapy
EAF Coelho, MA Chávez-Fumagalli… - Revista da Sociedade …, 2015 - SciELO Brasil
Phage display is a high-throughput subtractive proteomic technology used for the
generation and screening of large peptide and antibody libraries. It is based on the selection …
generation and screening of large peptide and antibody libraries. It is based on the selection …
Antigenicity and Protective Efficacy of a Leishmania Amastigote-specific Protein, Member of the Super-oxygenase Family, against Visceral Leishmaniasis
VT Martins, MA Chavez-Fumagalli… - PLoS neglected …, 2013 - journals.plos.org
Background The present study aimed to evaluate a hypothetical Leishmania amastigote-
specific protein (LiHyp1), previously identified by an immunoproteomic approach performed …
specific protein (LiHyp1), previously identified by an immunoproteomic approach performed …
Proteins selected in Leishmania (Viannia) braziliensis by an immunoproteomic approach with potential serodiagnosis applications for tegumentary leishmaniasis
MC Duarte, DC Pimenta… - Clinical and Vaccine …, 2015 - Am Soc Microbiol
The serodiagnosis of human tegumentary leishmaniasis (TL) presents some problems, such
as the low level of antileishmanial antibodies found in most of the patients, as well as the …
as the low level of antileishmanial antibodies found in most of the patients, as well as the …
Mimotope-Based Vaccines of Leishmania infantum Antigens and Their Protective Efficacy against Visceral Leishmaniasis
LE Costa, LR Goulart, NCJ Pereira, MIS Lima… - PloS one, 2014 - journals.plos.org
Background The development of cost-effective prophylactic strategies to prevent
leishmaniasis has become a high-priority. The present study has used the phage display …
leishmaniasis has become a high-priority. The present study has used the phage display …
Towards a More Precise Serological Diagnosis of Human Tegumentary Leishmaniasis Using Leishmania Recombinant Proteins
AP Souza, M Soto, JML Costa, VS Boaventura… - PLoS …, 2013 - journals.plos.org
Background Exposure to Leishmania induces a humoral immune response that can be used
as a marker of parasite exposure. Methodology/Principal Findings Herein, ELISA was used …
as a marker of parasite exposure. Methodology/Principal Findings Herein, ELISA was used …
A Leishmania-specific hypothetical protein expressed in both promastigote and amastigote stages of Leishmania infantum employed for the serodiagnosis of, and as …
VT Martins, MC Duarte, MA Chávez-Fumagalli… - Parasites & …, 2015 - Springer
Background LiHyV is an antigenic hypothetical protein present in both promastigote and
amastigote stages of Leishmania infantum, which was recently identified by an …
amastigote stages of Leishmania infantum, which was recently identified by an …
Mapping B-Cell Epitopes for the Peroxidoxin of Leishmania (Viannia) braziliensis and Its Potential for the Clinical Diagnosis of Tegumentary and Visceral …
The search toward the establishment of novel serological tests for the diagnosis of
leishmaniasis and proper differential diagnosis may represent one alternative to the invasive …
leishmaniasis and proper differential diagnosis may represent one alternative to the invasive …