[HTML][HTML] Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome
R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
Current and novel treatment options for obstructive sleep apnoea
W Randerath, J de Lange, J Hedner… - ERJ open …, 2022 - Eur Respiratory Soc
Obstructive sleep apnoea is a challenging medical problem due to its prevalence, its impact
on quality of life and performance in school and professionally, the implications for risk of …
on quality of life and performance in school and professionally, the implications for risk of …
A randomized controlled clinical trial exploring safety and tolerability of sulthiame in sleep apnea
J Hedner, K Stenlöf, D Zou, E Hoff… - American journal of …, 2022 - atsjournals.org
Rationale: Current therapies for obstructive sleep apnea (OSA) are limited by insufficient
efficacy, compliance, or tolerability. An effective pharmacological treatment for OSA is …
efficacy, compliance, or tolerability. An effective pharmacological treatment for OSA is …
Neural ventilatory drive decline as a predominant mechanism of obstructive sleep apnoea events
Background In the classic model of obstructive sleep apnoea (OSA), respiratory events
occur with sleep-related dilator muscle hypotonia, precipitating increased neural ventilatory …
occur with sleep-related dilator muscle hypotonia, precipitating increased neural ventilatory …
Pharmacotherapy for obstructive sleep apnea: targeting specific pathophysiological traits
E Perger, S Bertoli, C Lombardi - Expert Review of Respiratory …, 2023 - Taylor & Francis
Introduction The pathophysiology of obstructive sleep apnea (OSA) is multi-factorial and
complex. Varying OSA's pathophysiological traits have been identified, including pharyngeal …
complex. Varying OSA's pathophysiological traits have been identified, including pharyngeal …
Effect of phrenic nerve stimulation on patients with central sleep apnea: a meta-analysis
Y Wang, Y Huang, M Xia, M Salanitro, JF Kraemer… - Sleep Medicine …, 2023 - Elsevier
Patients with central sleep apnea (CSA) have a lower quality of life and higher morbidity and
mortality. Phrenic nerve stimulation (PNS) is a novel treatment for CSA that has been shown …
mortality. Phrenic nerve stimulation (PNS) is a novel treatment for CSA that has been shown …
Effects of acetazolamide on control of breathing in sleep apnea patients: Mechanistic insights using meta‐analyses and physiological model simulations
Obstructive and central sleep apnea affects~ 1 billion people globally and may lead to
serious cardiovascular and neurocognitive consequences, but treatment options are limited …
serious cardiovascular and neurocognitive consequences, but treatment options are limited …
[HTML][HTML] The pathogenesis of central and complex sleep apnea
EG Roberts, JR Raphelson, JE Orr… - Current neurology and …, 2022 - Springer
Purpose The purpose of this article is to review the recent literature on central apnea. Sleep
disordered breathing (SDB) is characterized by apneas (cessation in breathing), and …
disordered breathing (SDB) is characterized by apneas (cessation in breathing), and …
Positive airway pressure adherence and health care resource utilization in patients with obstructive sleep apnea and heart failure with reduced ejection fraction
A Malhotra, KV Cole, AS Malik, JL Pépin… - Journal of the …, 2023 - Am Heart Assoc
Background Obstructive sleep apnea (OSA) is a common comorbidity in patients with heart
failure, although current evidence is equivocal regarding the potential benefits of treating …
failure, although current evidence is equivocal regarding the potential benefits of treating …
Obstructive sleep apnea: personalizing CPAP alternative therapies to individual physiology
B Nokes, J Cooper, M Cao - Expert Review of Respiratory …, 2022 - Taylor & Francis
Introduction The recent continuous positive airway pressure (CPAP) crisis has highlighted
the need for alternative obstructive sleep apnea (OSA) therapies. This article serves to …
the need for alternative obstructive sleep apnea (OSA) therapies. This article serves to …