Roles, functions, and mechanisms of long non-coding RNAs in cancer
Y Fang, MJ Fullwood - Genomics, Proteomics and …, 2016 - academic.oup.com
Long non-coding RNAs (lncRNAs) play important roles in cancer. They are involved in
chromatin remodeling, as well as transcriptional and post-transcriptional regulation, through …
chromatin remodeling, as well as transcriptional and post-transcriptional regulation, through …
Paracrine mechanisms of mesenchymal stromal cells in angiogenesis
S Maacha, H Sidahmed, S Jacob… - Stem cells …, 2020 - Wiley Online Library
The role of the mesenchymal stromal cell‐(MSC‐) derived secretome is becoming
increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous …
increasingly intriguing from a clinical perspective due to its ability to stimulate endogenous …
Circulating noncoding RNAs as biomarkers of cardiovascular disease and injury
J Viereck, T Thum - Circulation research, 2017 - Am Heart Assoc
The discovery of thousands of noncoding RNAs (ncRNAs) has expanded our view on
mammalian genomes and transcriptomes, as well as their organization and regulation …
mammalian genomes and transcriptomes, as well as their organization and regulation …
The long noncoding RNA Wisper controls cardiac fibrosis and remodeling
R Micheletti, I Plaisance, BJ Abraham, A Sarre… - Science translational …, 2017 - science.org
Long noncoding RNAs (lncRNAs) are emerging as powerful regulators of cardiac
development and disease. However, our understanding of the importance of these …
development and disease. However, our understanding of the importance of these …
[HTML][HTML] CARMEN, a human super enhancer-associated long noncoding RNA controlling cardiac specification, differentiation and homeostasis
Long noncoding RNAs (lncRNAs) are emerging as important regulators of developmental
pathways. However, their roles in human cardiac precursor cell (CPC) remain unexplored …
pathways. However, their roles in human cardiac precursor cell (CPC) remain unexplored …
Non-coding RNA therapeutics for cardiac regeneration
A growing body of evidence indicates that cardiac regeneration after myocardial infarction
can be achieved by stimulating the endogenous capacity of cardiomyocytes (CMs) to …
can be achieved by stimulating the endogenous capacity of cardiomyocytes (CMs) to …
Non-coding RNAs in mesenchymal stem cell-derived extracellular vesicles: deciphering regulatory roles in stem cell potency, inflammatory resolve, and tissue …
Extracellular vesicles (EVs) are heterogeneous populations of nano-and micro-sized
vesicles secreted by various cell types. There is mounting evidence that EVs have …
vesicles secreted by various cell types. There is mounting evidence that EVs have …
Deficiency in the nuclear long noncoding RNA Charme causes myogenic defects and heart remodeling in mice
M Ballarino, A Cipriano, R Tita, T Santini… - The EMBO …, 2018 - embopress.org
Myogenesis is a highly regulated process that involves the conversion of progenitor cells
into multinucleated myofibers. Besides proteins and mi RNA s, long noncoding RNA s (lnc …
into multinucleated myofibers. Besides proteins and mi RNA s, long noncoding RNA s (lnc …
Assessment of the Cardiac Noncoding Transcriptome by Single-Cell RNA Sequencing Identifies FIXER, a Conserved Profibrogenic Long Noncoding RNA
P Aghagolzadeh, I Plaisance, R Bernasconi… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Cardiac fibroblasts have crucial roles in the heart. In particular, fibroblasts
differentiate into myofibroblasts in the damaged myocardium, contributing to scar formation …
differentiate into myofibroblasts in the damaged myocardium, contributing to scar formation …
Non-coding RNAs: update on mechanisms and therapeutic targets from the ESC Working Groups of Myocardial Function and Cellular Biology of the Heart
Vast parts of mammalian genomes are actively transcribed, predominantly giving rise to non-
coding RNA (ncRNA) transcripts including microRNAs, long ncRNAs, and circular RNAs …
coding RNA (ncRNA) transcripts including microRNAs, long ncRNAs, and circular RNAs …