The sirtuin family in health and disease
QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - Signal transduction and …, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
Potential adverse effects of resveratrol: A literature review
Due to its health benefits, resveratrol (RE) is one of the most researched natural
polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the …
polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the …
The therapeutic potential of resveratrol: a review of clinical trials
AY Berman, RA Motechin, MY Wiesenfeld… - NPJ precision …, 2017 - nature.com
Resveratrol is a nutraceutical with several therapeutic effects. It has been shown to mimic
effects of caloric restriction, exert anti-inflammatory and anti-oxidative effects, and affect the …
effects of caloric restriction, exert anti-inflammatory and anti-oxidative effects, and affect the …
Health benefits of resveratrol: Evidence from clinical studies
AP Singh, R Singh, SS Verma, V Rai… - Medicinal research …, 2019 - Wiley Online Library
Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …
Adipogenesis as a potential anti-obesity target: A review of pharmacological treatment and natural products
Obesity is recognized as a severe threat to overall human health and is associated with type
2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal …
2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal …
Sirtuins and NAD+ in the Development and Treatment of Metabolic and Cardiovascular Diseases
AE Kane, DA Sinclair - Circulation research, 2018 - Am Heart Assoc
The sirtuin family of nicotinamide adenine dinucleotide–dependent deacylases (SIRT1–7)
are thought to be responsible, in large part, for the cardiometabolic benefits of lean diets and …
are thought to be responsible, in large part, for the cardiometabolic benefits of lean diets and …
Anti-obesity effects of polyphenol intake: Current status and future possibilities
M Boccellino, S D'Angelo - International journal of molecular sciences, 2020 - mdpi.com
The prevalence of obesity has steadily increased worldwide over the past three decades.
The conventional approaches to prevent or treat this syndrome and its associated …
The conventional approaches to prevent or treat this syndrome and its associated …
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
MS Bonkowski, DA Sinclair - Nature reviews Molecular cell biology, 2016 - nature.com
Abstract The sirtuins (SIRT1–7) are a family of nicotinamide adenine dinucleotide (NAD+)-
dependent deacylases with remarkable abilities to prevent diseases and even reverse …
dependent deacylases with remarkable abilities to prevent diseases and even reverse …
Biological activities of stilbenoids
BC Akinwumi, KAM Bordun, HD Anderson - International journal of …, 2018 - mdpi.com
Stilbenoids are a group of naturally occurring phenolic compounds found in various plant
species. They share a common backbone structure known as stilbene, but differ in the …
species. They share a common backbone structure known as stilbene, but differ in the …
Antioxidant effects of resveratrol in the cardiovascular system
The antioxidant effects of resveratrol (3, 5, 4'‐trihydroxy‐trans‐stilbene) contribute
substantially to the health benefits of this compound. Resveratrol has been shown to be a …
substantially to the health benefits of this compound. Resveratrol has been shown to be a …