Radiation pneumonitis (RP) and radiation fibrosis (RF) are two dose-limiting toxicities of
radiotherapy (RT), especially for lung, and esophageal cancer. It occurs in 5–20% of …

Radiotherapy is a pivotal component in the curative treatment of patients with localised
cancer and isolated metastasis, as well as being used as a palliative strategy for patients …

External beam radiotherapy with photon beams is a highly accurate treatment modality, but
requires extensive quality assurance programs to confirm that radiation therapy will be or …

Background The purpose of this study was to introduce an experimental radiobiological
setup used for in vivo irradiation of a mouse leg target in multiple positions along a proton …

Background and purpose The effects of radiation on the heart are dependent on dose,
fractionation, overall treatment time, and pre-existing cardiovascular pathology. Murine …

Simple Summary An increasing number of cancer patients are treated with proton therapy.
Nevertheless, there are still open questions that require preclinical studies, for example …

Magnetic nanoparticle (MNP)-mediated hyperthermia (MH) coupled with radiation therapy
(RT) is a novel approach that has the potential to overcome various practical difficulties …

This Roadmap paper covers the field of precision preclinical x-ray radiation studies in
animal models. It is mostly focused on models for cancer and normal tissue response to …

Extraordinary normal tissue response to highly spatially fractionated X-ray beams has been
explored for over 25 years. More recently, alternative radiation sources have been …

Preclinical radiotherapy studies using small animals are an indispensable step in the
pathway from in vitro experiments to clinical implementation. As radiotherapy techniques …