[HTML][HTML] Multimodal molecular imaging in drug discovery and development

I Vermeulen, EM Isin, P Barton, B Cillero-Pastor… - Drug discovery today, 2022 - Elsevier
In addition to individual imaging techniques, the combination and integration of several
imaging techniques, so-called multimodal imaging, can provide large amounts of …

Advanced ultrasound methods to improve chronic kidney disease diagnosis

S Fleig, ZA Magnuska, P Koczera, J Salewski… - npj Imaging, 2024 - nature.com
Chronic kidney disease (CKD) affects 850 million people worldwide and is associated with
significant cardiovascular morbidity and mortality. Routine laboratory tests do not reflect …

Development and validation of CT-based radiomics signature for overall survival prediction in multi-organ cancer

VH Le, QH Kha, TNT Minh, VH Nguyen, VL Le… - Journal of Digital …, 2023 - Springer
The malignant tumors in nature share some common morphological characteristics.
Radiomics is not only images but also data; we think that a probability exists in a set of …

Evaluation of radiomics feature stability in abdominal monoenergetic photon counting CT reconstructions

H Tharmaseelan, LT Rotkopf, I Ayx, A Hertel… - Scientific reports, 2022 - nature.com
Feature stability and standardization remain challenges that impede the clinical
implementation of radiomics. This study investigates the potential of spectral reconstructions …

Reappraising the clinical usability of consolidation-to-tumor ratio on CT in clinical stage IA lung cancer

DW Yoon, CH Kim, S Hwang, YL Choi, JH Cho… - Insights into …, 2022 - Springer
Objectives Ground-glass opacity (GGO) on computed tomography is associated with
prognosis in early-stage non-small cell lung cancer (NSCLC) patients. However, the …

Biodistribution Assessment of a Novel 68Ga-Labeled Radiopharmaceutical in a Cancer Overexpressing CCK2R Mouse Model: Conventional and Radiomics …

AM Pavone, V Benfante, P Giaccone, A Stefano… - Life, 2024 - mdpi.com
The aim of the present study consists of the evaluation of the biodistribution of a novel 68Ga-
labeled radiopharmaceutical,[68Ga] Ga-NODAGA-Z360, injected into Balb/c nude mice …

CT and MRI radiomic features of lung cancer (NSCLC): comparison and software consistency

C Bortolotto, A Pinto, F Brero, G Messana… - European Radiology …, 2024 - Springer
Background Radiomics is a quantitative approach that allows the extraction of mineable
data from medical images. Despite the growing clinical interest, radiomics studies are …

Insights into radiomics: impact of feature selection and classification

A Perniciano, A Loddo, C Di Ruberto, B Pes - Multimedia Tools and …, 2024 - Springer
Radiomics is an innovative discipline in medical imaging that uses advanced quantitative
feature extraction from radiological images to provide a non-invasive method of interpreting …

Correlation of Radiomics with Treatment Response in Liver Metastases

L Mostafavi, F Homayounieh, F Lades, A Primak… - Academic …, 2024 - Elsevier
Rationale and Objectives To assess differences in radiomics derived from semi-automatic
segmentation of liver metastases for stable disease (SD), partial response (PR), and …

Tumor-infiltrating lymphocyte enrichment predicted by CT radiomics analysis is associated with clinical outcomes of non-small cell lung cancer patients receiving …

C Park, DY Jeong, Y Choi, YJ Oh, J Kim, J Ryu… - Frontiers in …, 2023 - frontiersin.org
Background Enrichment of tumor-infiltrating lymphocytes (TIL) in the tumor
microenvironment (TME) is a reliable biomarker of immune checkpoint inhibitors (ICI) in non …