Fungal secondary metabolites are defined by bioactive properties that ensure adaptation of
the fungus to its environment. Although some of these natural products are promising …

Fungi have evolved unique metabolic regulation mechanisms for adapting to the changing
environments. One of the key features of fungal adaptation is the production of secondary …

Fungi are well known for their ability to produce a multitude of natural products. On the one
hand their potential to provide beneficial antibiotics and immunosuppressants has been …

Fungal secondary metabolism has become an important research topic with great
biomedical and biotechnological value. In the postgenomic era, understanding the diversity …

DNA methylation is essential for epigenetic regulation of gene transcription and
development in many animals, plants and fungi. We investigated whether DNA methylation …

Trichoderma reesei is the industrial producer of cellulases and hemicellulases for
biorefinery processes. Their expression is obligatorily dependent on the function of the …

Epipolythiodioxopiperazines (ETPs) are fungal secondary metabolites that share a 2, 5‐
diketopiperazine scaffold built from two amino acids and bridged by a sulfide moiety …

The putative methyltransferase LaeA is a global regulator of metabolic and development
processes in filamentous fungi. We characterized the homologous laeA genes of the white …

Epigenetic and transcriptional control of gene expression must be coordinated in response
to external signals to promote alternative multicellular developmental programs. The …

Fungal fruiting bodies are complex, three-dimensional structures that arise from a less
complex vegetative mycelium. Their formation requires the coordinated action of many …