[HTML][HTML] Survivin: A molecular biomarker in cancer

PK Jaiswal, A Goel, RD Mittal - Indian Journal of Medical …, 2015 - journals.lww.com
Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases
and blocks cell death, is highly expressed in most cancers and is associated with a poor …

Survivin, a cancer target with an emerging role in normal adult tissues

S Fukuda, LM Pelus - Molecular cancer therapeutics, 2006 - AACR
Survivin, an inhibitor of apoptosis protein, is highly expressed in most cancers and
associated with chemotherapy resistance, increased tumor recurrence, and shorter patient …

Structural, functional and therapeutic biology of survivin

NK Sah, Z Khan, GJ Khan, PS Bisen - Cancer letters, 2006 - Elsevier
Survivin is a unique member of the inhibitor of apoptosis (IAP) protein family that interferes
with post-mitochondrial events including activation of caspases. Survivin regulates cell cycle …

Initial apoptosis is followed by increased proliferation of apoptosis‐resistant endothelial cells

S Sakao, L Taraseviciene‐Stewart, JD Lee… - The FASEB …, 2005 - Wiley Online Library
We have demonstrated that VEGF receptor blockade in combination with chronic hypoxia
causes in rats severe angioproliferative pulmonary hypertension (SAPH) associated with …

Pancreatic cancer: basic and clinical aspects

G Schneider, JT Siveke, F Eckel, RM Schmid - Gastroenterology, 2005 - gastrojournal.org
More than 30,000 people develop pancreatic adeno-carcinoma each year in the United
States, and almost all are expected to die from the disease. 1 The 5-year survival rate is 5 …

Targeted rod-shaped mesoporous silica nanoparticles for the co-delivery of camptothecin and survivin shRNA in to colon adenocarcinoma in vitro and in vivo

M Babaei, K Abnous, SM Taghdisi, S Taghavi… - European Journal of …, 2020 - Elsevier
Simultaneous drug and gene delivery to cancer cells has been introduced to provide
advantages of the synergistic effects of gene to sensitize the cancer cells to …

Survivin study: what is the next wave?

F Li - Journal of cellular physiology, 2003 - Wiley Online Library
Survivin, a novel member of inhibitor of apoptosis (IAP) protein family, is aberrantly
expressed in cancer but undetectable in normal, differentiated adult tissues. Current studies …

Survivin as a radioresistance factor, and prognostic and therapeutic target for radiotherapy in rectal cancer

F Rödel, J Hoffmann, L Distel, M Herrmann… - Cancer research, 2005 - AACR
Apoptosis levels have been shown to predict tumor response to preoperative
radiochemotherapy in rectal cancer. Recently, the prominent role of survivin, a structurally …

Molecular prognostic markers in pancreatic cancer: a systematic review

G Garcea, CP Neal, CJ Pattenden, WP Steward… - European journal of …, 2005 - Elsevier
Pancreatic cancer is one of the most lethal tumours of the gastrointestinal tract. The ability to
predict which patients would benefit most from surgical intervention and/or chemotherapy …

[HTML][HTML] Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

RJ Kelly, A Lopez-Chavez, D Citrin, JE Janik… - Molecular cancer, 2011 - Springer
Abstract Survivin (BIRC5), a member of the inhibitor of apoptosis protein (IAP) family that
inhibits caspases and blocks cell death is highly expressed in cancer and is associated with …