[HTML][HTML] Design, synthesis, antimycobacterial evaluation, and in silico studies of 3-(phenylcarbamoyl)-pyrazine-2-carboxylic acids

L Semelková, P Janošcová, C Fernandes, G Bouz… - Molecules, 2017 - mdpi.com
Pyrazinamide, the first-line antitubercular drug, has been regarded the basic component of
tuberculosis treatment for over sixty years. Researchers have investigated its effect on …

Inhibiting G protein coupled receptor 6 kinase polypeptides

AK Stewart, A Plekhov, R Greenhouse - US Patent 10,252,984, 2019 - Google Patents
(51) Int. CI. CO7D 403/10 (2006. 01) CO7D 221/18(2006. 01) CO7D 23734(2006. 01) CO7D
239/70(2006. 01) C07D 249/12(2006. 01) CO7D 285/135(2006. 01) C07D 295/13(2006. 01) …

Derivatives of cycloalkyl-and cycloalkenyl-1, 2-dicarboxylic acid compounds having formyl peptide receptor like-1 (FPRL-1) agonist or antagonist activity

RL Beard, JE Donello, V Vuligonda… - US Patent 8,618,163, 2013 - Google Patents
US8618163B2 - Derivatives of cycloalkyl- and cycloalkenyl-1,2-dicarboxylic acid compounds
having formyl peptide receptor like-1 (FPRL-1) agonist or antagonist activity - Google Patents …

Methods and pharmaceutical compositions of the treatment of autistic syndrome disorders

L Montagnier, C Skorupka, P Raymond… - US Patent …, 2018 - Google Patents
(51) Int. CI. A61K 31/7052 (2006. 01) A61K 31/4164 (2006. 01) A61K 31/4196 (2006. 01)
A61K 31/4184 (2006. 01) C12Q 1/68(2018. 01) A61K 31/65(2006. 01) C12Q 1/689(2018 …

Small molecule efflux pump inhibitors

PM Dunman, CE Blanchard - US Patent 10,471,028, 2019 - Google Patents
Small molecule efflux pump inhibitors are provided, as well as methods for their use in
treating infections. Also provided herein are methods of using the small molecule efflux …

Small molecule inhibitors of G protein coupled receptor 6 kinases polypeptides

AK Stewart, B Rich, N Sepetov, R Greenhouse… - US Patent …, 2018 - Google Patents
US9902739B2 - Small molecule inhibitors of G protein coupled receptor 6 kinases polypeptides
- Google Patents US9902739B2 - Small molecule inhibitors of G protein coupled receptor 6 …

Interaction energy calculation method, calculation device, and program

H Sato - US Patent 10,650,913, 2020 - Google Patents
A method, which includes: extracting one or more calculation-target water molecules that
influence at least interaction energy between the target molecule and some of the drug …

4-methoxy-n′-(2-(5-phenyl-1, 3, 4-oxadiazol-2-ylthio) acetoxy) benzimidamide as an antimicrobial compound

HMAEL Ahmed, MMK Ali, AAA Ahmed… - US Patent …, 2024 - Google Patents
US11891366B1 - 4-methoxy-n′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide
as an antimicrobial compound - Google Patents US11891366B1 - 4-methoxy-n′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide …

N′-(2-(5-(4-chlorophenyl)-1, 3, 4-oxadiazol-2-ylthio) acetoxy) benzimidamide as an antimicrobial compound

MMK Ali, HMAEL Ahmed, AAA Ahmed… - US Patent …, 2024 - Google Patents
US11919872B1 - N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide
as an antimicrobial compound - Google Patents US11919872B1 - N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide …

N'-(2-(5-(4-chlorophenyl)-1, 3, 4-oxadiazol-2-ylthio) acetoxy)-3, 4-dimethoxybenzimidamide as an antimicrobial compound

HMAEL Ahmed, MMK Ali, AAA Ahmed… - US Patent …, 2024 - Google Patents
US11912675B1 - N'-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-3,4-dimethoxybenzimidamide
as an antimicrobial compound - Google Patents US11912675B1 - N'-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-3,4-dimethoxybenzimidamide …