Evolving therapeutic landscape of advanced hepatocellular carcinoma
C Yang, H Zhang, L Zhang, AX Zhu… - Nature reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is one of the most common solid malignancies worldwide.
A large proportion of patients with HCC are diagnosed at advanced stages and are only …
A large proportion of patients with HCC are diagnosed at advanced stages and are only …
[HTML][HTML] The role of PI3K/AKT/mTOR signaling in hepatocellular carcinoma metabolism
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in
the world. Metabolic reprogramming is considered a new hallmark of cancer, but it remains …
the world. Metabolic reprogramming is considered a new hallmark of cancer, but it remains …
Molecular therapies and precision medicine for hepatocellular carcinoma
The global burden of hepatocellular carcinoma (HCC) is increasing and might soon surpass
an annual incidence of 1 million cases. Genomic studies have established the landscape of …
an annual incidence of 1 million cases. Genomic studies have established the landscape of …
[HTML][HTML] Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma
EJ Sun, M Wankell, P Palamuthusingam, C McFarlane… - Biomedicines, 2021 - mdpi.com
Despite advances in the treatment of cancers through surgical procedures and new
pharmaceuticals, the treatment of hepatocellular carcinoma (HCC) remains challenging as …
pharmaceuticals, the treatment of hepatocellular carcinoma (HCC) remains challenging as …
[HTML][HTML] Integrated proteogenomic characterization of HBV-related hepatocellular carcinoma
We performed the first proteogenomic characterization of hepatitis B virus (HBV)-related
hepatocellular carcinoma (HCC) using paired tumor and adjacent liver tissues from 159 …
hepatocellular carcinoma (HCC) using paired tumor and adjacent liver tissues from 159 …
[HTML][HTML] Molecular signaling pathways and therapeutic targets in hepatocellular carcinoma
M Dimri, A Satyanarayana - Cancers, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is a complex biological process and is often diagnosed at
advanced stages with no effective treatment options. With advances in tumor biology and …
advanced stages with no effective treatment options. With advances in tumor biology and …
Mechanisms of HBV-induced hepatocellular carcinoma
M Levrero, J Zucman-Rossi - Journal of hepatology, 2016 - Elsevier
Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through
direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …
direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …
Genetic landscape and biomarkers of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer-related death. Its
mortality has increased in Western populations, with a minority of patients diagnosed at …
mortality has increased in Western populations, with a minority of patients diagnosed at …
Liver transplantation for hepatocellular carcinoma: outcomes and novel surgical approaches
G Sapisochin, J Bruix - Nature reviews Gastroenterology & hepatology, 2017 - nature.com
Liver transplantation for hepatocellular carcinoma (HCC) is the best treatment option for
patients with early-stage tumours and accounts for∼ 20–40% of all liver transplantations …
patients with early-stage tumours and accounts for∼ 20–40% of all liver transplantations …
[HTML][HTML] Obesity-induced TNFα and IL-6 signaling: the missing link between obesity and inflammation—driven liver and colorectal cancers
L Kern, MJ Mittenbühler, AJ Vesting, AL Ostermann… - Cancers, 2019 - mdpi.com
Cancers | Free Full-Text | Obesity-Induced TNFα and IL-6 Signaling: The Missing Link between
Obesity and Inflammation—Driven Liver and Colorectal Cancers Next Article in Journal Effects …
Obesity and Inflammation—Driven Liver and Colorectal Cancers Next Article in Journal Effects …