Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

Recent progress in polymer research to tackle infections and antimicrobial resistance

MM Konai, B Bhattacharjee, S Ghosh… - …, 2018 - ACS Publications
Global health is increasingly being threatened by the rapid emergence of drug-resistant
microbes. The ability of these microbes to form biofilms has further exacerbated the scenario …

Biomimetic antimicrobial polymers: Recent advances in molecular design

C Ergene, K Yasuhara, EF Palermo - Polymer Chemistry, 2018 - pubs.rsc.org
The increasing prevalence of antibiotic-resistant bacterial infections, coupled with the
decline in the number of new antibiotic drug approvals, has created a therapeutic gap that …

Antimicrobial peptides and macromolecules for combating microbial infections: from agents to interfaces

L Yu, K Li, J Zhang, H Jin, A Saleem… - ACS Applied Bio …, 2022 - ACS Publications
Bacterial resistance caused by the overuse of antibiotics and the shelter of biofilms has
evolved into a global health crisis, which drives researchers to continuously explore …

Design of antimicrobial polymers

P Pham, S Oliver, C Boyer - Macromolecular Chemistry and …, 2023 - Wiley Online Library
Antibiotic resistance has become a critical issue, alarming the healthcare and agriculture
sectors worldwide. Thanks to rapid advancements in polymer science, antimicrobial …

Controlling macromolecular structures towards effective antimicrobial polymers

MS Ganewatta, C Tang - Polymer, 2015 - Elsevier
Drug resistance of pathogenic bacteria is a major global problem leading humanity towards
a pre-antibiotic era. Decline in the discovery of novel antibiotics and the lack of a resilient …

Positively charged polymers as promising devices against multidrug resistant gram-negative bacteria: A Review

S Alfei, AM Schito - Polymers, 2020 - mdpi.com
Antibiotic resistance has increased markedly in Gram-negative bacteria, causing severe
infections intractable with traditional drugs and amplifying mortality and healthcare costs …

Effect of hydrophobic groups on antimicrobial and hemolytic activity: Developing a predictive tool for ternary antimicrobial polymers

PT Phuong, S Oliver, J He, EHH Wong… - …, 2020 - ACS Publications
Antimicrobial polymers have emerged as a potential solution to the growing problem of
antimicrobial resistance. Although several studies have examined the effects of various …

The roadmap of antimicrobial polymeric materials in macromolecular nanotechnology

A Muñoz-Bonilla, M Fernández-García - European Polymer Journal, 2015 - Elsevier
Antimicrobial strategies combining polymer science and nanotechnology have attracted
tremendous interest in the last decade because of their great potential in many applications …

Synthetic random copolymers as a molecular platform to mimic host-defense antimicrobial peptides

H Takahashi, GA Caputo, S Vemparala… - Bioconjugate …, 2017 - ACS Publications
Synthetic polymers have been used as a molecular platform to develop host-defense
antimicrobial peptide (AMP) mimetics which are effective in killing drug-resistant bacteria. In …