The respiratory syncytial virus vaccine and monoclonal antibody landscape: the road to global access

J Terstappen, SF Hak, A Bhan, D Bogaert… - The Lancet Infectious …, 2024 - thelancet.com
Respiratory syncytial virus (RSV) is the second most common pathogen causing infant
mortality. Additionally, RSV is a major cause of morbidity and mortality in older adults (age≥ …

Respiratory syncytial virus infections in adults: a narrative review

JG Wildenbeest, DM Lowe, JF Standing… - The Lancet Respiratory …, 2024 - thelancet.com
Respiratory syncytial virus (RSV), an RNA virus spread by droplet infection that affects all
ages, is increasingly recognised as an important pathogen in adults, especially among older …

[HTML][HTML] Efficacy of Respiratory Syncytial Virus Vaccination to Prevent Lower Respiratory Tract Illness in Older Adults: A Systematic Review and Meta-Analysis of …

M Riccò, A Cascio, S Corrado, M Bottazzoli, F Marchesi… - Vaccines, 2024 - mdpi.com
A systematic review and meta-analysis was designed in order to ascertain the effectiveness
of respiratory syncytial virus (RSV) vaccination in preventing lower respiratory tract diseases …

[HTML][HTML] Public health impact of the adjuvanted RSVPreF3 vaccine for respiratory syncytial virus prevention among older adults in the United States

D Molnar, EM La, F Verelst, S Poston, J Graham… - Infectious Diseases and …, 2024 - Springer
Introduction Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract
disease in older adults, resulting in substantial morbidity and mortality. Methods This study …

Adjuvant system AS01: from mode of action to effective vaccines

F Roman, W Burny, MA Ceregido… - Expert Review of …, 2024 - Taylor & Francis
Introduction The use of novel adjuvants in human vaccines continues to expand as their
contribution to preventing disease in challenging populations and caused by complex …

Whole-Genome Sequencing and Genetic Diversity of Human Respiratory Syncytial Virus in Patients with Influenza-Like Illness in Sicily (Italy) from 2017 to 2023

F Tramuto, CM Maida, G Randazzo, V Guzzetta… - Viruses, 2024 - mdpi.com
Monitoring the genetic variability of human respiratory syncytial virus (hRSV) is of paramount
importance, especially for the potential implication of key antigenic mutations on the …

Safety and Immunogenicity of Respiratory Syncytial Virus Prefusion F Protein Vaccine when Co-administered with Adjuvanted Seasonal Quadrivalent Influenza …

R Clark, S Davies, J Labrador, P Loubet… - Clinical Infectious …, 2024 - academic.oup.com
Background We evaluated co-administration of adjuvanted seasonal quadrivalent influenza
vaccine (FLU-aQIV) and respiratory syncytial virus (RSV) prefusion F protein-based vaccine …

Respiratory syncytial virus: challenges in diagnosis and impact on the elderly: Recommendations from a multidisciplinary panel

L Michelin, N Bellei… - Human Vaccines & …, 2024 - Taylor & Francis
Respiratory syncytial virus (RSV) is an important cause of respiratory illness. While most
attention is paid to childhood infection, the RSV burden in adults≥ 60 y should also be …

Noninferior Immunogenicity and Consistent Safety of Respiratory Syncytial Virus Prefusion F Protein Vaccine in Adults 50–59 Years Compared to≥ 60 Years of Age

M Ferguson, TF Schwarz, SA Núñez… - Clinical Infectious …, 2024 - academic.oup.com
Background The adjuvanted respiratory syncytial virus (RSV) prefusion F protein–based
vaccine (RSVPreF3 OA) is approved in adults aged≥ 60 years. We evaluated RSVPreF3 …

[HTML][HTML] Differences Between RSV A and RSV B Subgroups and Implications for Pharmaceutical Preventive Measures

C Nuttens, J Moyersoen, D Curcio… - Infectious Diseases and …, 2024 - Springer
Introduction Understanding the differences between respiratory syncytial virus (RSV)
subgroups A and B provides insights for the development of prevention strategies and public …