Background The burden of malaria infection in sub-Saharan Africa among school-aged
children aged 5–15 years is underappreciated and represents an important source of …

Background Malaria causes significant morbidity and mortality worldwide. There are several
preventive measures that are currently employed, including insecticide-treated nets (ITNs …

INTRODUCTION Malaria remains a devastating disease, affecting 216 million people
annually, with 445,000 deaths occurring primarily in children under 5 years old. Malaria …

Background In high transmission settings, most school-aged children harbour malaria
parasites without showing symptoms, often leading to anaemia and possibly impaired …

Abstract Background Children in Kenya spend a substantial amount of time at school,
including at dawn and dusk when mosquitoes are active. With changing vector behaviour …

Background DSM265 is a selective inhibitor of Plasmodium dihydroorotate dehydrogenase
that fully protected against controlled human malarial infection (CHMI) by direct venous …

Anti-malarial drug resistance to chloroquine and sulfadoxine–pyrimethamine has spread
from Southeast Asia to Africa. Furthermore, the recent emergence of resistance to …

Background Intermittent preventive treatment (IPT) is a well established malaria control
intervention. Evidence that delivering IPT to schoolchildren could provide community-level …

ABSTRACT P218 is a highly selective dihydrofolate reductase inhibitor with potent in vitro
activity against pyrimethamine-resistant Plasmodium falciparum. This single-center …

Anemia is a multifactorial condition arising from inadequate nutrition, infection, chronic
disease, and genetic-related etiologies. Our aim was to assess the impact of nutrition …