A literature review of MTHFR (C677T and A1298C polymorphisms) and cancer risk
M Izmirli - Molecular biology reports, 2013 - Springer
Methlenetetrahydrofolate reductase (MTHFR) is one of the most important enzymes for folate
metabolism. This enzyme is mapped on chromosome 1, which is located at the end of the …
metabolism. This enzyme is mapped on chromosome 1, which is located at the end of the …
Host genetic profiling to increase drug safety in colorectal cancer from discovery to implementation
Adverse events affect the pharmacological treatment of approximately 90% of colorectal
cancer (CRC) patients at any stage of the disease. Chemotherapy including …
cancer (CRC) patients at any stage of the disease. Chemotherapy including …
MiR-22, regulated by MeCP2, suppresses gastric cancer cell proliferation by inducing a deficiency in endogenous S-adenosylmethionine
D Tong, J Zhang, X Wang, Q Li, L Liu, A Lu, B Guo… - Oncogenesis, 2020 - nature.com
This study investigated the effect of methyl-CpG-binding protein 2 (MeCP2) on miRNA
transcription. Our results of miRNA chip assay and ChIP-seq showed that MeCP2 inhibited …
transcription. Our results of miRNA chip assay and ChIP-seq showed that MeCP2 inhibited …
Genetic polymorphisms in MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) genes associated with pathological characteristics of prostate cancer in the …
A López-Cortés, G Jaramillo-Koupermann… - The American journal of …, 2013 - Elsevier
Introduction The methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR)
and MTR reductase (MTRR) enzymes act in the folate metabolism, which is essential in …
and MTR reductase (MTRR) enzymes act in the folate metabolism, which is essential in …
[HTML][HTML] The Frequency of the 677C> T and 1298A> C Polymorphisms in the Methylenetetrahydrofolate Reductase (MTHFR) Gene in the Population
Background: The gene for 5, 10-methylenetetrahydrofolate reductase (NAD (P) H) or
MTHFR gene encodes protein methylenetetrahydrofolate reductase (MTHFR), an enzyme …
MTHFR gene encodes protein methylenetetrahydrofolate reductase (MTHFR), an enzyme …
Identification and Characterization of CDH1 Germline Variants in Sporadic Gastric Cancer Patients and in Individuals at Risk of Gastric Cancer
Objective To screen and characterize germline variants for E-cadherin (CDH1) in non-
hereditary gastric cancer (GC) patients and in subjects at risk of GC. Methods 59 GCs, 59 …
hereditary gastric cancer (GC) patients and in subjects at risk of GC. Methods 59 GCs, 59 …
Pregnane X receptor, constitutive androstane receptor and hepatocyte nuclear factors as emerging players in cancer precision medicine
Great research effort has been focused on elucidating the contribution of host genetic
variability on pharmacological outcomes in cancer. Nuclear receptors have emerged as …
variability on pharmacological outcomes in cancer. Nuclear receptors have emerged as …
Dietary folate, one‐carbon metabolism‐related genes, and gastric cancer risk in Korea
Scope We evaluated the interactions between polymorphisms involved in one‐carbon
metabolism‐related genes and dietary folate intake in gastric cancer risk within the Korean …
metabolism‐related genes and dietary folate intake in gastric cancer risk within the Korean …
[HTML][HTML] Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer susceptibility
LZ Xia, Y Liu, XZ Xu, PC Jiang, G Ma… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To identify the association between methylenetetrahydrofolate reductase (MTHFR)
polymorphisms and gastric cancer (GC) susceptibility. METHODS: Systematic searches …
polymorphisms and gastric cancer (GC) susceptibility. METHODS: Systematic searches …
[HTML][HTML] MTHFR genetic polymorphism increases the risk of preterm delivery
Y Nan, H Li - International journal of clinical and experimental …, 2015 - ncbi.nlm.nih.gov
Aims: This study aimed to investigate the association between the methylene
tetrahydrofolate reductase (MTHFR) gene C677T and A1298C polymorphisms and …
tetrahydrofolate reductase (MTHFR) gene C677T and A1298C polymorphisms and …