Plasma proteomics identify biomarkers and pathogenesis of COVID-19
T Shu, W Ning, D Wu, J Xu, Q Han, M Huang, X Zou… - Immunity, 2020 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic is a global public health
crisis. However, little is known about the pathogenesis and biomarkers of COVID-19. Here …
crisis. However, little is known about the pathogenesis and biomarkers of COVID-19. Here …
[HTML][HTML] New insights into lipopolysaccharide inactivation mechanisms in sepsis
EG Pérez-Hernández, B Delgado-Coello… - Biomedicine & …, 2021 - Elsevier
The complex pathophysiology of sepsis makes it a syndrome with limited therapeutic options
and a high mortality rate. Gram-negative bacteria containing lipopolysaccharides (LPS) in …
and a high mortality rate. Gram-negative bacteria containing lipopolysaccharides (LPS) in …
Cholesteryl ester transfer protein and its inhibitors
Most of the cholesterol in plasma is in an esterified form that is generated in potentially
cardioprotective HDLs. Cholesteryl ester transfer protein (CETP) mediates bidirectional …
cardioprotective HDLs. Cholesteryl ester transfer protein (CETP) mediates bidirectional …
Inhibition of cholesteryl ester transfer protein preserves high-density lipoprotein cholesterol and improves survival in sepsis
Background: The high-density lipoprotein hypothesis of atherosclerosis has been
challenged by clinical trials of cholesteryl ester transfer protein (CETP) inhibitors, which …
challenged by clinical trials of cholesteryl ester transfer protein (CETP) inhibitors, which …
Effects of anti-IL-17 on inflammation, remodeling, and oxidative stress in an experimental model of asthma exacerbated by LPS
LN Camargo, RF Righetti, LRCRB Aristóteles… - Frontiers in …, 2018 - frontiersin.org
Inflammation plays a central role in the development of asthma, which is considered an
allergic disease with a classic Th2 inflammatory profile. However, cytokine IL-17 has been …
allergic disease with a classic Th2 inflammatory profile. However, cytokine IL-17 has been …
Cholesteryl ester transfer protein influences high-density lipoprotein levels and survival in sepsis
M Trinder, KR Genga, HJJ Kong, LL Blauw… - American journal of …, 2019 - atsjournals.org
Rationale: High-density lipoprotein (HDL) cholesterol (HDL-C) levels decline during sepsis,
and lower levels are associated with worse survival. However, the genetic mechanisms …
and lower levels are associated with worse survival. However, the genetic mechanisms …
Therapeutic effects of lentinan on inflammatory bowel disease and colitis‐associated cancer
Y Liu, J Zhao, Y Zhao, S Zong, Y Tian… - Journal of cellular …, 2019 - Wiley Online Library
In this study, we investigated the therapeutic potential of lentinan in mouse models of
inflammatory bowel disease (IBD) and colitis‐associated cancer (CAC). Lentinan decreased …
inflammatory bowel disease (IBD) and colitis‐associated cancer (CAC). Lentinan decreased …
Anti-inflammatory effects of diet and caloric restriction in metabolic syndrome
Background Weight loss in patients with metabolic syndrome has positive effects on
cardiovascular and type 2 diabetes risks, but its effects on peripheral cytokines and lipid …
cardiovascular and type 2 diabetes risks, but its effects on peripheral cytokines and lipid …
Novel role of CETP in macrophages: reduction of mitochondrial oxidants production and modulation of cell immune-metabolic profile
Plasma cholesteryl ester transfer protein (CETP) activity diminishes HDL-cholesterol levels
and thus may increase atherosclerosis risk. Experimental evidence suggests CETP may …
and thus may increase atherosclerosis risk. Experimental evidence suggests CETP may …
A novel role for CETP as immunological gatekeeper: raising HDL to cure sepsis?
LL Blauw, Y Wang, KW van Dijk… - Trends in Endocrinology & …, 2020 - cell.com
Raising HDL using cholesteryl ester transfer protein (CETP) inhibitors failed to show a
clinically relevant risk reduction of cardiovascular disease in clinical trials, inviting …
clinically relevant risk reduction of cardiovascular disease in clinical trials, inviting …