Benefits and harm of probiotics and synbiotics in adult critically ill patients. A systematic review and meta-analysis of randomized controlled trials with trial sequential …

ZY Lee, CCH Lew, A Ortiz-Reyes, JJ Patel, YJ Wong… - Clinical Nutrition, 2023 - Elsevier
Background & aims Several systematic reviews and meta-analyses of randomized
controlled trials concluded that probiotics administration in critically ill patients was safe and …

[HTML][HTML] Safety and efficacy of probiotic supplements as adjunctive therapies in patients with COVID-19: a systematic review and meta-analysis

J Zhu, T Pitre, C Ching, D Zeraatkar, S Gruchy - PLoS One, 2023 - journals.plos.org
Background and aims Oral probiotic supplementation may be a beneficial adjunctive
therapy for patients with symptomatic COVID-19. However, its safety and efficacy are …

[PDF][PDF] Harnessing the human microbiome: Probiotic and prebiotic interventions to reduce hospital-acquired infections and enhance immunity

AO Olatunji, JA Olaboye, CC Maha… - International Medical …, 2024 - researchgate.net
Harnessing the human microbiome: Probiotic and prebiotic interventions to reduce hospital-acquired
infections and enhance immuni Page 1 International Medical Science Research Journal, Volume 4 …

[HTML][HTML] Synbiotics and surgery: can prebiotics and probiotics affect inflammatory surgical outcomes?

K Trone, S Rahman, CH Green, C Venegas… - Current Nutrition …, 2023 - Springer
Abstract Purpose of Review Prebiotics, probiotics, and synbiotics have received increasing
attention over the years for their beneficial impact on the gut microbiome and for their …

[HTML][HTML] Gut microbiome-based therapeutics in critically ill adult patients—a narrative review

S He, F Lin, X Hu, P Pan - Nutrients, 2023 - mdpi.com
The gut microbiota plays a crucial role in the human microenvironment. Dysbiosis of the gut
microbiota is a common pathophysiological phenomenon in critically ill patients. Therefore …

Gut microbiome in sepsis

NJ Klingensmith, CM Coopersmith - Surgical Infections, 2023 - liebertpub.com
The gut has been hypothesized to be the “motor” of multiple organ dysfunction in sepsis.
Although there are multiple ways in which the gut can drive systemic inflammation …

Efficacy of probiotics or synbiotics in critically ill patients: a systematic review and meta-analysis

J Lou, S Cui, N Huang, G Jin, C Chen, Y Fan… - Clinical Nutrition …, 2023 - Elsevier
Background This latest systematic review and meta-analysis aim to examine the effects of
probiotic and synbiotic supplementation in critically ill patients. Methods Relevant articles …

[HTML][HTML] Why give my surgical patients probiotics

K Kotzampassi - Nutrients, 2022 - mdpi.com
Although there are various hypotheses on the health-promoting roles probiotic
supplementation play—via targeting the gut microbiota and/or regulating the systemic …

[HTML][HTML] What surgeon should know about probiotics

K Kotzampassi - Nutrients, 2022 - mdpi.com
Back in the 1980s, Fuller R, when working on gut flora, concluded that “there is good
evidence that the complex microbial flora present in the gastrointestinal tract... is effective in …

Trial sequential analysis in critical care medicine: The way forward

CCH Lew, ZY Lee, C Gluud - Critical Care Medicine, 2022 - journals.lww.com
We congratulate Sharif et al (1) for their interesting systematic review and meta-analysis,
published in a recent issue of Critical Care Medicine, of randomized clinical trials (RCTs) on …