Pulmonary manifestations of sickle cell disease

AK Siddiqui, S Ahmed - Postgraduate medical journal, 2003 - academic.oup.com
Pulmonary complications account for significant morbidity and mortality in patients with
sickle cell disease. Clinical lung involvement manifests in two major forms: the acute chest …

Sickle cell lung disease and sudden death: a retrospective/prospective study of 21 autopsy cases and literature review

JK Graham, M Mosunjac, RL Hanzlick… - The American journal …, 2007 - journals.lww.com
Sickle Cell Lung Disease and Sudden Death: A Retrospective/P... : The American Journal of
Forensic Medicine and Pathology Sickle Cell Lung Disease and Sudden Death: A …

Cardiopulmonary complications leading to premature deaths in adult patients with sickle cell disease

CD Fitzhugh, N Lauder, JC Jonassaint… - American journal of …, 2010 - Wiley Online Library
Sickle cell disease (SCD) is associated with early mortality. We sought to determine the
incidence, cause, and risk factors for death in an adult population of patients with SCD. All …

Patterns of arginine and nitric oxide in patients with sickle cell disease with vaso-occlusive crisis and acute chest syndrome

CR Morris, FA Kuypers, S Larkin… - Journal of pediatric …, 2000 - journals.lww.com
Purpose Our objective was to evaluate l-arginine and nitric oxide metabolite (NO x) levels in
children with sickle cell disease (SCD) at steady-state and during vaso-occlusive crisis …

Asthma in children with sickle cell disease and its association with acute chest syndrome

JM Knight-Madden, TS Forrester, NA Lewis… - Thorax, 2005 - thorax.bmj.com
Background: Pulmonary complications are a major cause of morbidity and mortality in sickle
cell disease (SCD). The relationship of asthma with SCD and acute chest syndrome (ACS) …

Prevalence and reversibility of lower airway obstruction in children with sickle cell disease

AC Koumbourlis, HJ Zar, A Hurlet-Jensen… - The Journal of …, 2001 - Elsevier
Objective: To determine the prevalence and reversibility of lower airway obstruction (LAO) in
children and adolescents with hemoglobin SS sickle cell disease (HbSS SCD). Study …

Towards a model of lung biomechanics: pulmonary kinematics via registration of serial lung images

TA Sundaram, JC Gee - Medical image analysis, 2005 - Elsevier
The lungs are highly elastic organs, composed of a variety of structures: vasculature,
airways and parenchyma. The unique mechanical properties of each of these structures …

Airway hyperreactivity detected by methacholine challenge in children with sickle cell disease

OY Ozbek, B Malbora, N Sen, AC Yazici… - Pediatric …, 2007 - Wiley Online Library
Recent studies have emphasized the presence of airway hyperreactivity (AHR) in children
with sickle cell disease (SCD). However, various tests for the detection of AHR have yielded …

A novel therapeutic approach to the treatment of scleroderma-associated pulmonary complications: safety and efficacy of combination therapy with imatinib and …

I Sabnani, MJ Zucker, ED Rosenstein, DA Baran… - …, 2009 - academic.oup.com
Objective. Scleroderma-related interstitial lung disease (SSc-ILD) has limited therapeutic
options due to unclear pathogenesis. Recently, PDGF receptor (PDGFR) amplification has …

[HTML][HTML] Evaluation of functional capacity for exercise in children and adolescents with sickle-cell disease through the six-minute walk test

SV Hostyn, WB de Carvalho, C Johnston, JAP Braga - Jornal de pediatria, 2013 - Elsevier
Objective To evaluate lung functional capacity (FC) for physical exercise in children and
adolescents with sickle cell disease (SCD) through the six-minute walk test (6MWT). Method …