[HTML][HTML] Efficacy of essential oils in pain: A systematic review and meta-analysis of preclinical evidence

D Scuteri, K Hamamura, T Sakurada… - Frontiers in …, 2021 - frontiersin.org
Background: The demand for essential oils (EOs) has been steadily growing over the years.
This is mirrored by a substantial increase in research concerned with EOs also in the field of …

Development of natural products for anti-PD-1/PD-L1 immunotherapy against cancer

MH Ri, J Ma, X Jin - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance The programmed cell death protein 1 (PD-1)/programmed
death-ligand 1 (PD-L1) immune checkpoint is one of the most promising therapeutic targets …

[HTML][HTML] The Computational Preventive Potential of the Rare Flavonoid, Patuletin, Isolated from Tagetes patula, against SARS-CoV-2

AM Metwaly, EB Elkaeed, BA Alsfouk, AM Saleh… - Plants, 2022 - mdpi.com
The rare flavonoid, patuletin, was isolated from the flowers of Tagetes patula growing in
Egypt. The rarity of the isolated compound inspired us to scrutinize its preventive effect …

Preparation and Characterization of Patuletin‐Loaded Chitosan Nanoparticles with Improved Selectivity and Safety Profiles for Anticancer Applications

AM Metwaly, AM Abdel-Raoof, AM Alattar… - Journal of …, 2023 - Wiley Online Library
Objective. This study aimed to investigate the preparation of patuletin‐encapsulated
chitosan nanoparticles (PT‐CS‐NPs) using the ionic gelation method, evaluate their …

A review of the botany, traditional uses, phytochemistry, and pharmacology of the Flos Inulae

L Yang, X Wang, A Hou, J Zhang, S Wang… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Plants of the genus Inula have long been used as an
ethnomedicine in Asia, Europe, and North America for its high medicinal value and health …

Carthamus tinctorius L.: a natural neuroprotective source for anti-Alzheimer's disease drugs

Y Liang, L Wang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Alzheimer's disease (AD) is a multicausal
neurodegenerative disease clinically characterized by generalized dementia. The …

[HTML][HTML] Plant-derived natural products targeting ion channels for pain

S Goyal, S Goyal, AE Goins, SRA Alles - Neurobiology of Pain, 2023 - Elsevier
Chronic pain affects approximately one-fifth of people worldwide and reduces quality of life
and in some cases, working ability. Ion channels expressed along nociceptive pathways …

Bupleurum falcatum L. alleviates nociceptive and neuropathic pain: Potential mechanisms of action

D Ahmadimoghaddam, M Zarei, S Mohammadi… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance In Iranian folkloric medicine, Bupleurum falcatum
L.(Chinese Thoroughwax) has been used as a selective analgesic remedy for several …

Intracerebroventricular microinjection of kaempferol on memory retention of passive avoidance learning in rats: involvement of cholinergic mechanism (s)

M Zarei, S Mohammadi, S Jabbari… - International Journal of …, 2019 - Taylor & Francis
Purpose of the study: Kaempferol (KM) is a flavonoid found in plant-derived foods and
medicinal plants. Recently, it is well established that KM plays a protective role to develop …

[HTML][HTML] Anticancer targets and signaling pathways activated by britannin and related pseudoguaianolide sesquiterpene lactones

C Bailly - Biomedicines, 2021 - mdpi.com
Sesquiterpene lactones (SLs) are abundant in plants and display a large spectrum of
bioactivities. The compound britannin (BRT), found in different Inula species, is a …