Publisher Summary This chapter discusses in vitro and in vivo antiviral activities of antibody.
Since experimentation is far easier in vitro, researchers have been sought to develop in vitro …

All replication-competent retroviruses contain three main reading frames, gag, pol and env,
which are used for the synthesis of structural proteins, enzymes and envelope proteins …

Ribonuclease L (RNase L) is an important effector of the innate antiviral response. Mutations
or variants that impair function of RNase L, particularly R462Q, have been proposed as …

Chronic fatigue syndrome (CFS) is a serious systemic illness of unknown cause. A recent
study identified DNA from a xenotropic murine leukemia virus-related virus (XMRV) in …

Four isoforms of human fibroblast growth factor 2 (FGF-2) result from alternative initiations of
translation at three CUG start codons and one AUG start codon. Here we characterize a new …

FBL-3 is a highly immunogenic murine leukemia of C57BL/6 origin induced by Friend
murine leukemia virus (MuLV). Immunization of C57BL/6 mice with FBL-3 readily elicits …

The genomic retroviral RNA is the messenger for the translation of the gag and pol genes
encoding the precursors to the major structural proteins and enzymes, respectively, of the …

Pathogenic retroviruses have evolved multiple means for evading host restriction factors
such as apolipoprotein B editing complex (APOBEC3) proteins. Here, we show that murine …

Feline leukemia virus (FeLV) is one of the most prevalent infectious diseases in domestic
cats. Although different commercial vaccines are available, none of them provides full …

Gammaretroviruses, such as murine leukemia viruses (MLVs), encode, in addition to the
canonical Gag, Pol, and Env proteins that will form progeny virus particles, a protein called …