[HTML][HTML] Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration
Control and elimination of the parasitic disease schistosomiasis relies on mass
administration of praziquantel. Whilst these programmes reduce infection prevalence and …
administration of praziquantel. Whilst these programmes reduce infection prevalence and …
Scratching the itch: updated perspectives on the schistosomes responsible for swimmer's itch around the world
Although most studies of digenetic trematodes of the family Schistosomatidae dwell on
representatives causing human schistosomiasis, the majority of the 130 identified species of …
representatives causing human schistosomiasis, the majority of the 130 identified species of …
Integrating genomic and epidemiologic data to accelerate progress toward schistosomiasis elimination
The global community has adopted ambitious goals to eliminate schistosomiasis as a public
health problem, and new tools are needed to achieve them. Mass drug administration …
health problem, and new tools are needed to achieve them. Mass drug administration …
Schistosome W-linked genes inform temporal dynamics of sex chromosome evolution and suggest candidate for sex determination
M Elkrewi, MA Moldovan, MAL Picard… - Molecular Biology and …, 2021 - academic.oup.com
Schistosomes, the human parasites responsible for snail fever, are female-heterogametic.
Different parts of their ZW sex chromosomes have stopped recombining in distinct lineages …
Different parts of their ZW sex chromosomes have stopped recombining in distinct lineages …
Genome-wide analysis of Schistosoma mansoni reveals limited population structure and possible praziquantel drug selection pressure within Ugandan hot-spot …
Populations within schistosomiasis control areas, especially those in Africa, are
recommended to receive regular mass drug administration (MDA) with praziquantel (PZQ) …
recommended to receive regular mass drug administration (MDA) with praziquantel (PZQ) …
Population genomics of helminth parasites
Next generation sequencing technologies have facilitated a shift from a few targeted loci in
population genetic studies to whole genome approaches. Here, we review the types of …
population genetic studies to whole genome approaches. Here, we review the types of …
Cryptic population structure and transmission dynamics uncovered for Schistosoma mansoni populations by genetic analyses
Patterns of diversity in pathogen genomes provide a window into the spatiotemporal spread
of disease. In this study, we tested the hypothesis that Schistosoma mansoni parasites form …
of disease. In this study, we tested the hypothesis that Schistosoma mansoni parasites form …
Comparative and population genomic analyses of the parasitic blood flukes
D Berger - 2022 - repository.cam.ac.uk
The etiological agents of schistosomiasis are snail-vectored, waterborne, parasitic
trematodes of the genus Schistosoma. Schistosomes are considered a considerable public …
trematodes of the genus Schistosoma. Schistosomes are considered a considerable public …
Genome-wide analysis of Schistosoma mansoni reveals population structure and praziquantel drug selection pressure within Ugandan hot-spot communities
Populations within schistosomiasis control areas, especially those in Africa, are
recommended to receive regular mass drug administration (MDA) with praziquantel (PZQ) …
recommended to receive regular mass drug administration (MDA) with praziquantel (PZQ) …
Prospects for genomic surveillance for selection in schistosome parasites
Schistosomiasis is a neglected tropical disease caused by multiple parasitic Schistosoma
species, and which impacts over 200 million people globally, mainly in low-and middle …
species, and which impacts over 200 million people globally, mainly in low-and middle …