PrP genetics in ruminant transmissible spongiform encephalopathies
W Goldmann - Veterinary research, 2008 - hal.science
Scrapie, bovine spongiform encephalopathy (BSE), and chronic wasting disease (CWD) are
prion diseases in ruminants with considerable impact on animal health and welfare. They …
prion diseases in ruminants with considerable impact on animal health and welfare. They …
[HTML][HTML] State-of-the-art review of goat TSE in the European Union, with special emphasis on PRNP genetics and epidemiology
Scrapie is a fatal, neurodegenerative disease of sheep and goats. It is also the earliest
known member in the family of diseases classified as transmissible spongiform …
known member in the family of diseases classified as transmissible spongiform …
Identification of seven haplotypes of the caprine PrP gene at codons 127, 142, 154, 211, 222 and 240 in French Alpine and Saanen breeds and their association with …
F Barillet, D Mariat, Y Amigues… - Journal of General …, 2009 - microbiologyresearch.org
In sheep, susceptibility to scrapie is mainly influenced by polymorphisms of the PrP gene. In
goats, there are to date few data related to scrapie susceptibility association with PrP gene …
goats, there are to date few data related to scrapie susceptibility association with PrP gene …
Identification of prion protein gene polymorphisms in goats from Italian scrapie outbreaks
PL Acutis, A Bossers, J Priem… - Journal of general …, 2006 - microbiologyresearch.org
Susceptibility to scrapie in sheep is influenced by polymorphisms of the prion protein (PrP)
gene, whereas no strong association between genetics and scrapie has yet been …
gene, whereas no strong association between genetics and scrapie has yet been …
[HTML][HTML] Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom
W Goldmann, K Ryan, P Stewart, D Parnham… - Veterinary …, 2011 - Springer
The application of genetic breeding programmes to eradicate transmissible spongiform
encephalopathies in goats is an important aim for reasons of animal welfare as well as …
encephalopathies in goats is an important aim for reasons of animal welfare as well as …
[HTML][HTML] Potential scrapie-associated polymorphisms of the prion protein gene (PRNP) in Korean native black goats
SK Kim, YC Kim, SY Won, BH Jeong - Scientific Reports, 2019 - nature.com
Small ruminants, including sheep and goats are natural hosts of scrapie, and the
progression of scrapie pathogenesis is strongly influenced by polymorphisms in the prion …
progression of scrapie pathogenesis is strongly influenced by polymorphisms in the prion …
PrP gene polymorphisms in Cyprus goats and their association with resistance or susceptibility to natural scrapie
P Papasavva-Stylianou, O Windl, G Saunders… - The Veterinary …, 2011 - Elsevier
In contrast to scrapie in sheep, the genetic basis of susceptibility to scrapie in goats is not
well understood. To study the association of prion protein (PrP) alleles with susceptibility to …
well understood. To study the association of prion protein (PrP) alleles with susceptibility to …
Caprine PRNP polymorphisms at codons 171, 211, 222 and 240 in a Greek herd and their association with classical scrapie
The association between PRNP variation and scrapie incidence was investigated in a highly
affected Greek goat herd. Four mutations were identified at codons 171Q/R, 211R/Q, 222Q/K …
affected Greek goat herd. Four mutations were identified at codons 171Q/R, 211R/Q, 222Q/K …
Histidine at codon 154 of the prion protein gene is a risk factor for Nor98 scrapie in goats
S Colussi, G Vaccari, C Maurella… - Journal of General …, 2008 - microbiologyresearch.org
Prion protein gene (PRNP) polymorphisms are involved in modulating the appearance of
atypical/Nor98 scrapie in sheep, with the alleles AHQ and AF141RQ strongly associated …
atypical/Nor98 scrapie in sheep, with the alleles AHQ and AF141RQ strongly associated …
[HTML][HTML] Comparative Susceptibility of Sheep of Different Origins, Breeds and PRNP Genotypes to Challenge with Bovine Spongiform Encephalopathy and Scrapie
F Houston, W Goldmann, J Foster, L González… - PloS one, 2015 - journals.plos.org
Sheep are natural hosts of the prion disease, scrapie. They are also susceptible to
experimental challenge with various scrapie strains and with bovine spongiform …
experimental challenge with various scrapie strains and with bovine spongiform …