[HTML][HTML] Epstein Barr virus: development of vaccines and immune cell therapy for EBV-associated diseases
X Cui, CM Snapper - Frontiers in Immunology, 2021 - frontiersin.org
Epstein-Barr virus (EBV) is the first human tumor virus discovered and is strongly implicated
in the etiology of multiple lymphoid and epithelial cancers. Each year EBV associated …
in the etiology of multiple lymphoid and epithelial cancers. Each year EBV associated …
Immunotherapeutic approaches in EBV-associated nasopharyngeal carcinoma
W Li, X Duan, X Chen, M Zhan, H Peng… - Frontiers in …, 2023 - frontiersin.org
Epstein–Barr virus (EBV) was the first tumor virus in humans. Nasopharyngeal carcinoma
(NPC) accounts for approximately 60% of the 200,000 new tumor cases caused by EBV …
(NPC) accounts for approximately 60% of the 200,000 new tumor cases caused by EBV …
[HTML][HTML] Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins
CM Bollard, S Gottschalk, V Torrano… - Journal of Clinical …, 2014 - ncbi.nlm.nih.gov
Purpose Tumor cells from approximately 40% of patients with Hodgkin or non-Hodgkin
lymphoma express the type II latency Epstein-Barr virus (EBV) antigens latent membrane …
lymphoma express the type II latency Epstein-Barr virus (EBV) antigens latent membrane …
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients
T-cell immunotherapy that takes advantage of Epstein-Barr virus (EBV)–stimulated immunity
has the potential to fill an important niche in targeted therapy for EBV-related cancers. To …
has the potential to fill an important niche in targeted therapy for EBV-related cancers. To …
Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem …
Viral infection or reactivation remains a major cause of morbidity and mortality after
allogeneic stem cell transplantation. We now show that infusions of single cytotoxic T …
allogeneic stem cell transplantation. We now show that infusions of single cytotoxic T …
Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma
CU Louis, K Straathof, CM Bollard… - Journal of …, 2010 - journals.lww.com
Patients with recurrent or refractory Epstein Barr Virus (EBV)-positive nasopharyngeal
carcinoma (NPC) continue to have poor outcomes. Our earlier Phase I dose escalation …
carcinoma (NPC) continue to have poor outcomes. Our earlier Phase I dose escalation …
Phase I trial of recombinant modified vaccinia ankara encoding Epstein–Barr viral tumor antigens in nasopharyngeal carcinoma patients
Epstein–Barr virus (EBV) is associated with several malignancies including nasopharyngeal
carcinoma, a high incidence tumor in Chinese populations, in which tumor cells express the …
carcinoma, a high incidence tumor in Chinese populations, in which tumor cells express the …
Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer
CM Bollard, S Gottschalk, AM Leen… - Blood, The Journal …, 2007 - ashpublications.org
Abstract Epstein-Barr virus (EBV)–associated tumors developing in immunocompetent
individuals present a challenge to immunotherapy, since they lack expression of …
individuals present a challenge to immunotherapy, since they lack expression of …
HLA-A*02 is associated with a reduced risk and HLA-A*01 with an increased risk of developing EBV+ Hodgkin lymphoma
M Niens, RF Jarrett, B Hepkema… - Blood, The Journal …, 2007 - ashpublications.org
Previous studies showed that the HLA class I region is associated with Epstein-Barr virus
(EBV)–positive Hodgkin lymphoma (HL) and that HLA-A is the most likely candidate gene in …
(EBV)–positive Hodgkin lymphoma (HL) and that HLA-A is the most likely candidate gene in …
Identification of hexon-specific CD4 and CD8 T-cell epitopes for vaccine and immunotherapy
AM Leen, A Christin, M Khalil, H Weiss, AP Gee… - Journal of …, 2008 - Am Soc Microbiol
Adenoviral infections in the immunocompromised host are associated with significant
morbidity and mortality. Although the adoptive transfer of adenovirus-specific T cells may …
morbidity and mortality. Although the adoptive transfer of adenovirus-specific T cells may …