The Gut-brain Connection and Episodic Migraine: an Update

L Nguyen, N Hindiyeh, S Ray, RE Vann… - Current Pain and …, 2023 - Springer
Purpose of review Historical evidence suggests a shared underlying etiology for migraine
and gastrointestinal (GI) disorders that involves the gut-brain axis. Here we provide narrative …

Formulation and evaluation of self-nanoemulsifying drug delivery system derived tablet containing sertraline

AB Nair, B Singh, J Shah, S Jacob, B Aldhubiab… - Pharmaceutics, 2022 - mdpi.com
Being a biopharmaceutics classification system class II drug, the absorption of sertraline
from the gut is mainly limited by its poor aqueous solubility. The objective of this …

Role of MALDI-MSI in combination with 3D tissue models for early stage efficacy and safety testing of drugs and toxicants

CE Spencer, LE Flint, CJ Duckett, LM Cole… - Expert Review of …, 2020 - Taylor & Francis
ABSTRACT Introduction: Three-dimensional (3D) cell cultures have become increasingly
important materials to investigate biological processes and drug efficacy and toxicity. The …

A review on the colours, flavours and shapes used in paediatric 3D printed oral solid dosage forms

M Vlachou, A Siamidi, C Protopapa… - RPS Pharmacy and …, 2023 - academic.oup.com
Objectives This review aims at gleaning the currently available research reports that relate to
3D printlets for paediatric patients and especially the excipients used to produce various …

A Physiologically Based Pharmacokinetic (PBPK) Study to Assess the Adjuvanticity of Three Peptides in an Oral Vaccine

L Saldanha, Ü Langel, N Vale - Pharmaceutics, 2024 - mdpi.com
Following up on the first PBPK model for an oral vaccine built for alpha-tocopherol, three
peptides are explored in this article to verify if they could support an oral vaccine formulation …

[PDF][PDF] Development and Characterization of Silk Fibroin-based Oral Films Containing Turmeric Extract as Dietary

ME Uslu, O Bayraktar - Biointerface Res. Appl. Chem, 2022 - researchgate.net
Dietary supplements have extreme importance. Due to the easily degradable nature of these
supplements, the development and application of carrier systems in food technologies seem …

Characterization of Prototype Gummy Formulations Provides Insight into Setting Quality Standards

OA Adeleke, S Abedin - AAPS PharmSciTech, 2024 - Springer
Gummy formulations are considered suitable alternatives to traditional oral dosage forms
like tablets and capsules due to their merits that include chewability, softness/flexibility …

[PDF][PDF] Design of experiment based formulation optimization of chitosan-coated nano-liposomes of progesterone for effective oral delivery

P Dehariya, R Soni, SK Paswan… - Journal of Applied …, 2023 - academia.edu
The aim of this research was to design and develop chitosan-coated nano-liposomes of
progesterone for its safe and effective oral delivery through the vesicular system providing …

A New Approach for Characterizing the Thixotropic Properties of Gel Formulations as Sprayable Agents Based on Rheological Analysis

T Terukina, Y Uchiyama, F Kikuma, S Fukumitsu… - AAPS …, 2022 - Springer
The present study evaluated the rheological properties of gel formulations composed of the
thixotropic peptide amphiphile, palmitoyl-glycine-histidine (Pal-GH), and the thickener …

Versatile Hydrogels in Regenerative Medicine

Y Li, P Su, Y Wang, T Ye, G Nowaczyk… - Polymeric Biomaterials for …, 2023 - Springer
Hydrogels, as the most typical polymer materials with three-dimensional network structures,
have attracted wide attention owing to their outstanding features such as high-water content …