Since first described in the early 1900s, Alzheimer's disease (AD) has risen exponentially in
prevalence and concern. Research still drives to understand the etiology and pathogenesis …

Alcohol consumption is common in Western countries and has been increasing in older
adults. Latest figures from Great Britain suggest 75% of those over 65 years drink, an …

Data collected from clinical trials and cohort studies, such as dementia studies, are often
high-dimensional, censored, heterogeneous and contain missing information, presenting …

Importance The impact of serial changes in alcohol consumption on dementia risk has rarely
been investigated to date. Objective To investigate the association of comprehensive …

Importance Substantial heterogeneity and uncertainty exist in the observed associations
between alcohol consumption and dementia. Objective To assess the association between …

Background Dementia is a globally increasing health issue and since no cure is currently
available, prevention is crucial. The consumption of alcohol is a controversially discussed …

AimsLifestyle interventions are an important and viable approach for preventing cognitive
deficits. However, the results of studies on alcohol, coffee and tea consumption in relation to …

Background Understanding the long-term health effects of low to moderate alcohol
consumption is important for establishing thresholds for minimising the lifetime risk of harm …

Background Previous conventional epidemiological studies found a J-shape relationship
between alcohol consumption and dementia, but this result was subject to confounding …

Abstract Background Apolipoprotein E (APOE)-4 isoform, reelin, and clusterin share very–
low-density liporeceptor and apolipoprotein E receptor 2 receptors and are related to …