Functional ultrasound neuroimaging

G Montaldo, A Urban, E Macé - Annual Review of Neuroscience, 2022 - annualreviews.org
Functional ultrasound (fUS) is a neuroimaging method that uses ultrasound to track changes
in cerebral blood volume as an indirect readout of neuronal activity at high spatiotemporal …

Whole-brain functional ultrasound imaging in awake head-fixed mice

C Brunner, M Grillet, A Urban, B Roska, G Montaldo… - Nature …, 2021 - nature.com
Most brain functions engage a network of distributed regions. Full investigation of these
functions thus requires assessment of whole brains; however, whole-brain functional …

Silencing dentate newborn neurons alters excitatory/inhibitory balance and impairs behavioral inhibition and flexibility

H Li, R Tamura, D Hayashi, H Asai, J Koga, S Ando… - Science …, 2024 - science.org
Adult neurogenesis confers the hippocampus with unparalleled neural plasticity, essential
for intricate cognitive functions. The specific influence of sparse newborn neurons (NBNs) in …

Contribution of excitatory and inhibitory neuronal activity to BOLD fMRI

HS Moon, H Jiang, TT Vo, WB Jung… - Cerebral …, 2021 - academic.oup.com
The BOLD fMRI response in the cortex is often assumed to reflect changes in excitatory
neural activity. However, the contribution of inhibitory neurons to BOLD fMRI is unclear …

Whole-brain mapping of effective connectivity by fMRI with cortex-wide patterned optogenetics

S Kim, HS Moon, TT Vo, CH Kim, GH Im, S Lee, M Choi… - Neuron, 2023 - cell.com
Functional magnetic resonance imaging (fMRI) with optogenetic neural manipulation is a
powerful tool that enables brain-wide mapping of effective functional networks. To achieve …

[HTML][HTML] MP-PCA denoising of fMRI time-series data can lead to artificial activation “spreading”

FF Fernandes, JL Olesen, SN Jespersen, N Shemesh - NeuroImage, 2023 - Elsevier
MP-PCA denoising has become the method of choice for denoising MRI data since it
provides an objective threshold to separate the signal components from unwanted thermal …

Applications in awake animal magnetic resonance imaging

CF Ferris - Frontiers in neuroscience, 2022 - frontiersin.org
There are numerous publications on methods and applications for awake functional MRI
across different species, eg, voles, rabbits, cats, dogs, and rhesus macaques. Each of these …

Where do we stand on fMRI in awake mice?

F Mandino, S Vujic, J Grandjean, EMR Lake - Cerebral cortex, 2024 - academic.oup.com
Imaging awake animals is quickly gaining traction in neuroscience as it offers a means to
eliminate the confounding effects of anesthesia, difficulties of inter-species translation (when …

[HTML][HTML] Combined resting state-fMRI and calcium recordings show stable brain states for task-induced fMRI in mice under combined ISO/MED anesthesia

B Pradier, L Wachsmuth, N Nagelmann, D Segelcke… - NeuroImage, 2021 - Elsevier
For fMRI in animal models, the combination of low-dose anesthetic, isoflurane (ISO), and the
sedative medetomidine (MED) has recently become an advocated regimen to achieve …

Simultaneous functional magnetic resonance and optoacoustic imaging of brain‐wide sensory responses in mice

Z Chen, I Gezginer, MA Augath, YH Liu, R Ni… - Advanced …, 2023 - Wiley Online Library
Functional magnetic resonance imaging (fMRI) has massively contributed to the
understanding of mammalian brain function. However, the origin and interpretation of the …