Standard-free bioanalytical approach for absolute quantitation of drug metabolites utilizing biosynthesis of reciprocal radio and stable isotopologues and its …

Y Gong, J Chen, Y Shi, HK Lim, N Weng… - Analytical …, 2017 - ACS Publications
The following work describes a combined enzymatic and bioanalytical method that permits
absolute quantitation of metabolites in biological samples without the requirement for …

Bifunctionalized isotopologs as calibrants for standard‐free quantitation of drug metabolites in plasma by liquid chromatography coupled with radiometry and mass …

Y Gong, J Chen, HK Lim, N Weng… - Biomedical …, 2022 - Wiley Online Library
The reported method involves a novel workflow that eliminates the need for authentic
reference standards for the quantitation of drug metabolites in biological samples using a …