The interaction of Rebeccamycin with calf thymus (ctDNA) in the absence and presence of
H1 was investigated by molecular dynamics, multi-spectroscopic, and cellular techniques …

Prostate cancer (PCa) is a major cause of mortality and morbidity in men. Available
therapies yield limited outcome. We explored anti-PCa activity in a polyphenol-rich fraction …

The binding of drugs to nucleic acids, proteins, lipids, amino acids, and other biological
receptors is necessary for the transportation of drugs. However, various side effects may …

The influence of 2, 2, 2-trifluoroethanol (TFE) on the micellar properties of ionic surfactants
hexadecyltrimethylammonium bromide (CTAB), hexadecyltrimethylammonium p …

The present study aims to elucidate the anti-cancer, antimicrobial activity of synthesized
halogenated chalcones (1f, 1h, 1i) and their molecular interaction with calf thymus DNA. All …

Background Heat shock response (HSR), a component of cellular protein quality control
mechanisms, is defective in different neurodegenerative conditions such as Parkinson's …

In this study, we have inspected the interaction amongst ibuprofen sodium salt (NaIB) drug
and pharmaceutical excipients TX-45 (nonionic surfactant) using a tensiometric method in …

The study of the interactions of drug molecules with genetic materials plays a key role
underlying the development of new drugs for many life-threatening diseases in …

Studying the binding interaction between biological macromolecules and small molecules
has formed the core of different research aspects. The interaction of palbociclib with calf …

The interactions of actinomycin D (ActD) anticancer drug with two bile salts of different
hydrophobicity (sodium cholate (NaC) and sodium deoxycolate (NaDC) and the influence of …