The caffeic acid scaffold, which is abundant in nature, is extremely versatile and is found in a
number of biologically active molecules. The purpose of this review is to provide an …

Caffeic acid phenethyl ester (CAPE), as one of the main active ingredients of the natural
product propolis, shows the unique biological activities such as anti-tumor, anti-oxidation …

Isothiocyanates exhibit various biological characteristics, including antimicrobial, anti-
inflammatory, and anticancer properties. Their significance extends to synthetic chemistry …

Three new benzazole isothiocyanate (BzITC) fluorescent dyes, 2-(5′-isothiocyanate-2′-
hydroxyphenyl) benzoxazole, 2-(5′-isothiocyanate-2′-hydroxyphenyl) benzimidazole and …

We extended the previously described dynamic pharmacophore model studies of HIV-1
integrase (IN) by considering more key residues in the active site, including Mg2+. First, we …

Three new benzazole isothiocyanate fluorescent dyes, 2-(4′-isothiocyanate-2′-
hydroxyphenyl) benzoxazole, 2-(4′-isothiocyanate-2′-hydroxyphenyl) benzothiazole and …

Reactions of thiocarbonyl fluoride derived from cheap, readily available, and widely used
CF3SiMe3, elemental sulfur, and KF with secondary amines and primary amines at room …

A highly efficient, selective, and rapid transformation of primary amines and diamines to
isothiocyanates and cyclic thioureas is disclosed. As opposed to established approaches …

We present here a dynamic receptor-based pharmacophore model representing the
complementary features of the active site region of HIV-1 integrase (IN), which was …

Caffeic acid and its derivatives are already known to possess a wide range of biological
activities. We have developed quantitative structure–activity relationships (QSARs) for …