MicroRNAome genome: a treasure for cancer diagnosis and therapy
I Berindan‐Neagoe, PC Monroig… - CA: a cancer journal …, 2014 - Wiley Online Library
The interplay between abnormalities in genes coding for proteins and noncoding
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …
microRNAs (miRNAs) has been among the most exciting yet unexpected discoveries in …
MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy
AL Kasinski, FJ Slack - Nature Reviews Cancer, 2011 - nature.com
In normal cells multiple microRNAs (miRNAs) converge to maintain a proper balance of
various processes, including proliferation, differentiation and cell death. miRNA …
various processes, including proliferation, differentiation and cell death. miRNA …
Ovarian cancers: genetic abnormalities, tumor heterogeneity and progression, clonal evolution and cancer stem cells
Four main histological subtypes of ovarian cancer exist: serous (the most frequent),
endometrioid, mucinous and clear cell; in each subtype, low and high grade. The large …
endometrioid, mucinous and clear cell; in each subtype, low and high grade. The large …
Tumour angiogenesis regulation by the miR-200 family
The miR-200 family is well known to inhibit the epithelial–mesenchymal transition,
suggesting it may therapeutically inhibit metastatic biology. However, conflicting reports …
suggesting it may therapeutically inhibit metastatic biology. However, conflicting reports …
miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response
B Mateescu, L Batista, M Cardon, T Gruosso… - Nature medicine, 2011 - nature.com
Although there is evidence that redox regulation has an essential role in malignancies, its
impact on tumor prognosis remains unclear. Here we show crosstalk between oxidative …
impact on tumor prognosis remains unclear. Here we show crosstalk between oxidative …
[HTML][HTML] miR-214 as a key hub that controls cancer networks: small player, multiple functions
MicroRNAs are short regulatory RNAs that are able to post-transcriptionally modulate gene
expression and that have crucial roles in the control of physiological and pathological …
expression and that have crucial roles in the control of physiological and pathological …
The role of microRNAs in ovarian cancer
Y Kinose, K Sawada, K Nakamura… - BioMed research …, 2014 - Wiley Online Library
Ovarian cancer is the most lethal of malignant gynecological tumors. Its lethality may be due
to difficulties in detecting it at an early stage and lack of effective treatments for patients with …
to difficulties in detecting it at an early stage and lack of effective treatments for patients with …
miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression
H Tang, M Deng, Y Tang, X Xie, J Guo, Y Kong… - Clinical Cancer …, 2013 - AACR
Purpose: The purpose of this study was to investigate the clinicopathologic significance and
potential role of miR-200b and miR-200c in the development and progression of gastric …
potential role of miR-200b and miR-200c in the development and progression of gastric …
Dysregulation of circulating microRNAs and prediction of aggressive prostate cancer
BACKGROUND It is becoming increasingly evident that microRNAs (miRNAs) are
associated with the development and progression of prostate cancer (PCa). METHODS We …
associated with the development and progression of prostate cancer (PCa). METHODS We …
miR-200c: a versatile watchdog in cancer progression, EMT, and drug resistance
Abstract MicroRNAs (miRNAs) are 20–22-nucleotide small endogenous non-coding RNAs
which regulate gene expression at post-transcriptional level. In the last two decades …
which regulate gene expression at post-transcriptional level. In the last two decades …