Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary vascular disease
characterized by progressive pulmonary artery pressure elevation, increased pulmonary …

Introduction Kidney-type glutaminase (GLS1), a key enzyme controlling the hydrolysis of
glutamine to glutamate to resolve the 'glutamine addiction'of cancer cells, has been shown …

Pulmonary arterial hypertension (PAH) is a progressive disease that significantly endangers
human health, where metabolism may drive pathogenesis: a shift from mitochondrial …

Abstract m6A (N6‑methyladenosine) is the most common and abundant apparent
modification in mRNA of eukaryotes. The modification of m6A is regulated dynamically and …

Objective and design Post-traumatic urethral stricture is a clinical challenge for both patients
and clinicians. Targeting glutamine metabolism to suppress excessive activation of urethral …

Objective: Regulatory T cells (Tregs) are critical immune modulators to maintain immune
homeostasis and limit pulmonary hypertension (PH). This study was aimed to identify Treg …

Opinion statement Relapse after chemotherapy and hematopoietic stem cell transplantation
leads to adverse prognosis for acute myeloid leukemia (AML) patients. As a “conditionally …

Prolactin (PRL) is a polypeptide hormone that is mainly synthesized and secreted by the
lactotroph cells of the pituitary. There are two main isoforms of PRL: 23‐kDa PRL (named full …

Copper is one of the predominant water pollutants. Excessive exposure to copper can cause
harm to animal health, affecting the central nervous system and causing blood …

Pulmonary artery endothelial cells (PAECs) are a major contributor to hypoxic pulmonary
hypertension (PH) due to the possible roles of reactive oxygen species (ROS). However, the …