Advances in nanoparticles as anticancer drug delivery vector: need of this century

I Ali, SD Mukhtar, HS Ali, MT Scotti… - Current Pharmaceutical …, 2020 - ingentaconnect.com
Background: Nanotechnology has contributed a great deal to the field of medical science.
Smart drugdelivery vectors, combined with stimuli-based characteristics, are becoming …

[PDF][PDF] Role of computer-aided drug design in the discovery and development of new medicinal agents a review

D Purohit, M Makhija, P Pandey, S Kumar, S Kumar… - Int J Pharm Sci, 2018 - jmpas.com
Drug design and development is a time consuming and costly process. Nowadays,
computer-aided drug design approaches are usually used to improve drug discovery and …

[HTML][HTML] Synthesis of hydrazides of heterocyclic amines and their antimicrobial and spasmolytic activity

DA Berillo, MA Dyusebaeva - Saudi Pharmaceutical Journal, 2022 - Elsevier
Un unsolvable issue of a significant number increase of drug multi resistant strains of
microorganisms including Mycobacterium tuberculosis force researchers for continuous …

Teloxantron inhibits the processivity of telomerase with preferential DNA damage on telomeres

N Maciejewska, M Olszewski, J Jurasz… - Cell Death & …, 2022 - nature.com
Telomerase reactivation is one of the hallmarks of cancer, which plays an important role in
cellular immortalization and the development and progression of the tumor. Chemical …

How to achieve better results using PASS-based virtual screening: Case study for kinase inhibitors

PV Pogodin, AA Lagunin, AV Rudik… - Frontiers in …, 2018 - frontiersin.org
Discovery of new pharmaceutical substances is currently boosted by the possibility of
utilization of the Synthetically Accessible Virtual Inventory (SAVI) library, which includes …

Synthesis, Antimicrobial Properties, and Inhibition of Catalase Activity of 1, 4‐Naphtho‐and Benzoquinone Derivatives Containing N‐, S‐, O‐Substituted

S Kurban, NG Deniz, C Sayil, M Ozyurek… - Heteroatom …, 2019 - Wiley Online Library
A series of new 1, 4‐naphtho‐and benzoquinone derivatives possessing N‐, S‐, O‐
substituted groups which has not been reported yet has been synthesized from 2, 3‐dichloro …

Novel 2-Amino-1, 4-Naphthoquinone Derivatives Induce A549 Cell Death through Autophagy

HY Tan, FM Liang, WJ Zhang, Y Zhang, JH Cui, YY Dai… - Molecules, 2023 - mdpi.com
A series of 1, 4-naphthoquinone derivatives containing were synthesized as anti-cancer
agents and the crystal structure of compound 5a was confirmed by X-ray diffraction. In …

9, 10-Anthraquinone dithiocarbamates as potential pharmaceutical substances with pleiotropic actions: Computerized prediction of biological activity and …

MV Stasevich, VI Zvarich, VP Novikov… - Pharmaceutical …, 2020 - Springer
The pleiotropic pharmacological actions of 9, 10-anthraquinone dithiocarbamates were
studied. The Way2Drug web portal was used to establish that cytotoxic, antiviral, and …

Anthra[1,2-d][1,2,3]triazine-4,7,12(3H)-triones as a New Class of Antistaphylococcal Agents: Synthesis and Biological Evaluation

V Zvarych, M Stasevych, V Novikov, E Rusanov… - Molecules, 2019 - mdpi.com
The development and spread of resistance of human pathogenic bacteria to the action of
commonly used antibacterial drugs is one of the key problems in modern medicine. One of …

Three-component coupling of boronic acids, amines, and carbon disulfide by a heterogeneous catalyst of copper (II) embedded in a highly porous and magnetic Schiff …

N Keshavarzi, M Kohestanian, A Sabzevari… - Research on Chemical …, 2023 - Springer
In this work, the mesoporous magnetic heterogeneous catalyst was synthesized by
anchoring copper (II) onto the nitrogen-rich poly (melamine) Schiff base networks magnetic …