Diabetes mellitus is a common metabolic disorder that is caused by a deficit in the
production of (type 1) or response to (type 2) insulin. Diabetes mellitus is characterized by a …

With respect to their genome and their structure, the human hepatitis B virus (HBV) and
hepatitis C virus (HCV) are complete different viruses. However, both viruses can cause an …

Inflammatory granulocytes are characterized by an oxidative burst, which may promote
oxidative stress and lipid modification both in affected tissues and on a systemic level. On …

Excessive fructose (Fru) consumption has been reported to favor nonalcoholic fatty liver
disease (NAFLD). However, the molecular mechanism is still elusive, lacking effective …

The deregulation of autophagy is involved in liver regeneration. Here, we investigated the
role of autophagy in the regulation of liver regeneration after partial hepatectomy (PHx) and …

High-dose alcohol misuse induces multiple noxious cardiac effects, including myocyte
hypertrophy and necrosis, interstitial fibrosis, decreased ventricular contraction and ventricle …

The present study aimed to analyze the antioxidant and hepatoprotective efficacy of
watercress extract against liver fibrosis induced by CCl 4 (0.8 mL/kg, ip) in an in vivo rat …

Advanced medical devices, treatments and therapies demand an understanding of the role
of interfacial properties on the cellular response. This is particularly important in the …

The antioxidant function induced by Nrf2 protects the liver from damage. We found a novel
Nrf2 activator named compound 25 via structural modification of compound 1 we previously …

Liver cirrhosis is the result of an uncontrolled fibrogenetic process, due to the activation and
subsequent differentiation into myofibroblasts of the hepatic stellate cells (HSC). It is known …